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Introduction: Klotho and dipeptidyl peptidase-4 (DPP4) are two proteins that modulate inflammatory pathways. We investigated the association between circulating klotho and DPP4 activity and their relationship with inflammatory cytokines, miR-29a, and miR-195 in Alzheimer disease (AD). Methods: This study was conducted on 16 AD patients and 16 healthy age-matched controls. Plasma levels of tumo...
Introduction: Alzheimer’s disease (AD) is the most common cause of dementia worldwide. Mild cognitive impairment (MCI) is often the prodromal stage to AD. Most patients with MCI harbor the pathologic changes of AD and demonstrate transition to AD at a rate of 10–15% per year. Accumulating evidence indicates that the asymmetry changes of left and right brain have happened in the early stage of A...
به علت گسترش روزمره در شبکه های ارتباطاتی بی سیم، تلاش برای بالا بردن قابلیت اطمینان و سرعت ارسال در این کانال ها مورد توجه مراکز تحقیقاتی و پژوهشگران قرار گرفته است. استفاده از دایورسیتی مشارکتی با بهره گیری از رله، برای ارسال یا ارسال مجدد اطلاعات، باعث بهبود قابلیت اطمینان می شود. با انتخاب رله مناسب، می توان پارامترهای کلیدی سیستم، افزایش قابلیت اطمینان و سرعت ارسال را در شبکه های بی سیم، ب...
Classically, ascending aortic dissection (AD) presents as sudden, severe chest pain that is tearing type and radiates to the back. Herein, we present a rare case of severe aortic regurgitation with silent ascending AD, which had no chest pain symptoms. The aortic valve apparatus probably masked this AD; therefore, it was not detected by echocardiography and during the surgery.
Background and objective: Insulin and its receptor are located in the central nervous system where it regulates many important processes such as neural proliferation, apoptosis, synaptic transmission, neuronal survival, synaptic plasticity, learning and memory. Alzheimer's disease (AD) is characterized by the accumulation of extracellular amyloid-β (Aβ) plaques, and intracellular aggregation of...
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