BACKGROUND For TDM of mycophenolate acid (MPA), the Roche Total Mycophenolic Acid® assay based on the inhibition of recombinant inosine monophosphate dehydrogenase (IMPDH) has been shown to be a simple and reliable alternative to chromatographic methods. We have adapted this assay on the ABX Pentra 400 analyzer (HORIBA). OBJECTIVE To investigate the analytical performances of the Roche Total ...

Metagenetics is a rapid and taxonomically comprehensive method for revealing community structures within environmental samples, based on large amounts of sequence data produced by high-throughput sequencers. Because community structures of planktonic copepods are important in the ocean owing to their high diversity and abundance, a metagenetic analysis of the 28S D2 region using Roche 454 was p...

http://dx.doi.org/10.1016/j.jnnfm.2015.02.006 0377-0257/ 2015 Elsevier B.V. All rights reserved. ⇑ Corresponding author at: LSPM, University Paris-Nord, Sorbonne-Paris-Cité, France. E-mail addresses: [email protected] (I.R. Ionescu), [email protected] (A. Mangeney), [email protected] (F. Bouchut), O.Roche@opgc. univ-bpclermont.fr (O. Roche). Ioan R. Ionescu a,b,⇑, Anne Mangeney , ...

Employment or Leadership: None declared. Consultant or Advisory Role: A.S. Jaffe, Beckman Coulter, Critical Diagnostics, Inverness Medical, Radiometer, Pfizer, and Amgen. Stock Ownership: None declared. Honoraria: A.S. Jaffe, Roche and Abbott Laboratories. Research Funding: A.K. Saenger, Roche Diagnostics; G.G. Klee, Beckman Coulter; A.S. Jaffe, Beckman Coulter. Expert Testimony: None declared....

BACKGROUND Homogeneous LDL-cholesterol methods from Genzyme, Reference Diagnostics, Roche, and Sigma were evaluated for precision, accuracy, and specificity for LDL in the presence of abnormal lipoproteins. METHODS Each homogeneous method was performed by a Roche/Hitachi 911 according to the vendors' instructions, and the results were compared with the beta-quantification reference method. We...

INTRODUCTION Total 25-hydroxyvitamin D [25(OH)D] is the most reliable indicator of vitamin D status. In this study, we compared two automated immunoassay methods, the Abbott Architect 25-OH Vitamin D assay and the Roche Cobas Vitamin D total assay, with the liquid chromatography-tandem mass spectrometry (LC-MS/MS). MATERIALS AND METHODS One hundred venous blood samples were randomly selected ...