Background Individuals with Phelan-McDermid syndrome (PMS) present a wide range of diagnoses: autism spectrum disorder, intellectual disability, or schizophrenia. Differences in the genetic background could explain these different neurodevelopmental trajectories. However, more parsimonious hypothesis is to consider that they may be same phenotypic entity. Catatonic disturbances occasionally rep...

The cerebellum can be viewed as supporting two distinct aspects of motor execution related to a) motor coordination and the sequence that imparts such movement temporal coherence and b) the reorganization of ongoing movement when a motor execution error occurs. The former has been referred to as "motor time binding" as it requires that the large numbers of motoneurons involved be precisely acti...

Diffusion tensor tractography (DTT) is useful for exploring the state of the corticospinal tract (CST). An accurate estimation of the integrity of the CST in the early stage of a cerebral infarct would enable a determination of motor recovery. DTT was performed to classify CST integrity following a corona radiata infarct to evaluate if the procedure could characterize the motor outcome of the a...

هدف از این تحقیق تعیین مناطق دارای پتانسیل حضور چشمة آب زیرزمینی و اولویت‌بندی عوامل مؤثر در آن، با استفاده روش حداکثر آنتروپی (مدل MaxEnt)، سیستم اطلاعات جغرافیایی سنجش دور است. حاضر، چهارده شاخص تأثیرگذار شامل شاخص‌های توپوگرافیکی، زمین‌شناسی، اقلیمی، هیدرولوژیکی کاربری اراضی همچنین، جدید ارتفاع سطح نزدیک‌ترین زهکش (HAND) شده ابتدا، شاخص‌ها به دو بخش توپوگرافیکی سایر تقسیم شدند نقشة براساس آن...

یکی از مهم‌ترین مدهای حمل‌ونقل عمومی شبکة مترو است که تأثیر بسزایی در کاهش ترافیک و آلودگی هوا دارد. ازدیگرسو، با توجه به هزینه‌های سرسام‌آور راه‌اندازی مترو، توسعة مرحله‌به‌مرحله بهره‌برداری یک خط اجرای خطوط دیگر به‌دست مدیران شهری مورد است. بنابراین، هدف این تحقیق بررسی میزان دسترسی متروی اصفهان افق 1410، رویکرد عدالت مکانی، دو جنبة افقی عمودی پنج طبقة اجتماعی، استفاده شاخص‌های ضریب جینی، منح...

It has been demonstrated that passive cycling training can modulate the H-reflex spinal pathways in an animal model with complete spinal cord transection and in humans with complete spinal cord injury. The aim of this study was to understand if a similar modulation can be induced in hemiparetic patients. This aspect can be crucial in stroke rehabilitation because a recalibration of activity in ...

OBJECTIVE To determine factors associated with motor recovery of the upper extremity after repetitive transcranial magnetic stimulation (rTMS) treatment in stroke patients. METHODS Twenty-nine patients with subacute stroke participated in this study. rTMS was applied to the hand motor cortex for 10 minutes at a 110% resting motor threshold and 10 Hz frequency for two weeks. We evaluated the b...

Attention-deficit/hyperactivity disorder (ADHD) is commonly associated with disordered or disturbed sleep. The relationships of ADHD with sleep problems, psychiatric comorbidities and medications are complex and multidirectional. Evidence from published studies comparing sleep in individuals with ADHD with typically developing controls is most concordant for associations of ADHD with: hypopnea/...

OBJECTIVE To explore the strength of the association between gait speed and community ambulation and whether this association is significantly distorted by other variables. DESIGN Cross-sectional study conducted 3 years after stroke. SUBJECTS A total of 102 patients after first-ever stroke following inpatient rehabilitation who are now living in the community. METHODS Community ambulation...

BACKGROUND Commercial off-the-shelf computer gaming devices have been making inroads into the rehabilitation arena, with the objective of making therapeutic exercise fun and contextual. One such device is the Nintendo Wii. Published clinical studies evaluating its acceptance, potential benefits and side-effects in the rehabilitation of patients with post-stroke weakness are few in number. OBJ...