➢ With more complex research questions and query enhancements, functionality is continuously tested ➢ A specific query or set of queries are defined & test plans are developed ➢ Menu-Driven Queries in PopMedNet allow for theoretically limitless query complexity ➢ We create patients to meet our test cases in an Excel document adhering to the PCORnet Common Data Model ➢ We assign fake identifiers...

Result A range of pubertal risk factors significantly moderated the relationship between temperaments and ED severity. In particular, the relationship between TCI-Novelty Seeking and ED severity was found to be positively moderated by a negative attitude toward menstruation (p<0.01) and negatively moderated by earlier breast development (p<0.05). Similarly, the relationships between TCI-Harm Av...

OBJECTIVE To assess off-label use of the topical calcineurin inhibitors (TCIs), tacrolimus and pimecrolimus, in children during periods before and after regulatory action by the US Food and Drug Administration (FDA) in 2005. METHODS We identified new pediatric (age <20 years) users of topical tacrolimus or pimecrolimus in US Medicaid from 2001 to 2009, and examined the annual rate of drug use...

BACKGROUND Although surgery and anesthesia induce immunesuppression, remains largely unknown whether various anesthetic techniques have different immunosuppressive effects on cancer patients. Therefore, the aim of this study was to investigate the influence of total intravenous anesthesia with target-controlled infusion (TIVA-TCI) and balanced inhalation anesthesia (BAL) on the peri-operative l...

information was not included in the Methods section of our article. In contrast, however, BIS was relatively low at 3 mg ml of TCI. Although the TCI system does not predict plasma propofol concentration completely, a BIS monitor can be used during general anaesthesia. Remifentanil, however, affects the EEG characteristics during propofol anaesthesia. Therefore, we also wanted to know how remife...

Much research has been devoted to quantifying optimal or unacceptable climate conditions both generally and for specific tourism segments or activities over the last 10 years. This knowledge is not incorporated in the Tourism Climate Index (TCI), which has also been subject to other substantial critiques. To more accurately assess the climatic suitability of destinations for leisure tourism, th...

Transcutaneous immunization (TCI) is a new technique that uses the application of vaccine antigens in a solution on the skin to induce potent antibody responses without systemic or local toxicity. We have previously shown that cholera toxin (CT), a potent adjuvant for oral and nasal immunization, can induce both serum and mucosal immunoglobulin G (IgG) and IgA and protect against toxin-mediated...