Telomere length is dynamic in many organisms. Genetic screens that identify mutants with altered telomere lengths are essential if we are to understand how telomere length is regulated in vivo. In Tetrahymena thermophila, telomeres become long at 30 degrees, and growth rate slows. A slow-growing culture with long telomeres is often overgrown by a variant cell type with short telomeres and a rap...

Candidate plasticity-related gene 15 (cpg15) encodes a protein that regulates dendritic and axonal arbor growth and synaptic maturation. In the present study, we investigated the potential role of CPG15 in regulating the neuronal network re-establishment after ischemic brain injury. In the mouse model with transient global ischemia (TGI), CPG15 transcripts and proteins were determined using RT-...

Thermal-gravitational instability (TGI) is studied in the protogalactic environment. We extend our previous work, where we found that dense clumps first form out of hot background gas by thermal instability and later a small fraction of them grow to virialized clouds of mass Mc & 6×10 6 M⊙ by gravitational infall and merging. But these clouds have large angular momentum, so they would be diffic...

Abstract Chimeric antigen receptor (CAR)-T therapy has yielded impressive clinical results in hematological malignancies and it is a promising approach for solid tumor treatment. However, toxicity concern hampering its broader use. In selecting lead CAR-T candidate against the oncofetal glypican 3 (GPC3), we employed strategy to manage profile by single-chain variable fragment with reduced affi...

This research focused on the current demand for sleep products, analyzed healthy products in today's society and recognized importance of further visual communication users products. also function structure hardware software quantitatively analyzing their TGI index penetration rate. The relationship between them information was explored. situation part APP analyzed. design strategy highlighting...

• TGI composed of Green-NIR is the best spectral index for blackgrass weed. Random forest applied weed mapping with an accuracy 93%. Both and spatial information used classification. Algorithms are validated by UAV multispectral dataset. Accurate a prerequisite site-specific management to enable sustainable agriculture. This work aims analyse (spectrally) in wheat fields integrating Unmanned Ae...