Generation of cell diversity in the vertebrate central nervous system starts during gastrulation stages in the ectodermal germ layer and involves specialized cell groups, such as the organizer located at the midbrain-hindbrain boundary (MHB). Mutations in the zebrafish no isthmus (noi) gene alter development of the MHB, and affect the pax2.1 gene (formerly pax(zf-b)). Analysis of the structure ...

Silicon substrate losses and non-linearities were the limiting characteristics of Si-based MOSFET technologies to provide low-power and low-cost solutions to the mobile RF device market. Thanks to the trap-rich Silicon-on-Insulator (SOI) substrate invented at UCL and developed in collaboration with the French company SOITEC, RF SOI is becoming a mainstream technology which is implemented in all...

BACKGROUND The modern society primarily relies on petroleum and natural gas for the production of fuels and chemicals. One of the major commodity chemicals 1,2-propanediol (1,2-PDO), which has an annual production of more than 0.5 million tons in the United States, is currently produced by chemical processes from petroleum derived propylene oxide, which is energy intensive and not sustainable. ...

BACKGROUND 1,3-propanediol (PDO) is a substantially industrial metabolite used in the polymer industry. Although several natural PDO production hosts exist, e.g. Klebsiella sp., Citrobacter sp. and Clostridium sp., the PDO yield on glycerol is insufficient for an economically viable bio-process. Enhancing this yield via strain improvement can be achieved by disconnecting the production and grow...

This paper studied the construction of Pomology Domain Ontology (PDO), and the realization of PDO-based query system. First, an approach to build PDO based on Agriculture Science Thesaurus (AST) was proposed, which consists of confirming core concepts, adding the properties of concepts, confirming the relationships between concepts, adding the instances of concepts, and representing domain onto...

Această lucrare examinează literatura de specialitate cu privire la integrarea furnizorilor în realizarea de produse noi şi contribuie cu o cercetare empirică pentru a demonstra că diferenţierea tehnologică, performanţele afacerilor, inovarea şi comunicarea dintre companii şi furnizorii lor sunt pozitiv asociate cu nivelul de integrare al furnizorilor în realizarea de produse noi. În final, est...