RYOTA HOKARI,1 SOICHIRO MIURA,2 HITOSHI FUJIMORI,1 SEIICHIRO KOSEKI,1 YOSHIKAZU TSUZUKI,1 HIROYUKI KIMURA,1 HAJIME HIGUCHI,1 HIROSHI SERIZAWA,1 D. NEIL GRANGER,3 AND HIROMASA ISHII1 1Department of Internal Medicine, School of Medicine, Keio University, Tokyo 160-8582; 2Second Department of Internal Medicine, National Defense Medical College, Saitama 359-8513, Japan; and 3Department of Molecular...

Cyanobacteria are able to produce several metabolites that have toxic effects on humans and animals. Among these cyanotoxins, the hepatotoxic microcystins (MC) occur frequently. The intracellular MC content produced by two strains of Microcystis aeruginosa, PCC7806 and PCC7820, and its production kinetics during the culture time were studied in order to elucidate the conditions that favour the ...

Our objective was to determine if the presence of metabolic complications (MC) conveyed an additional risk for left ventricular (LV) dysfunction in people with HIV. HIV⁺ and HIV⁻ men and women were categorized into four groups: (1) HIV⁺ with MC (43±7 years, n=64), (2) HIV⁺ without MC (42±7 years, n=59), (3) HIV⁻ with MC (44±8 years, n=37), or (4) HIV⁻ controls without MC (42±8 years, n=41). All...

In this study, we investigated the kinetic aspects of the microcystin (MC) transfer from Planktothrix rubescens to Daphnia magna by carrying out exposure experiments in small simple mesocosms. We hypothesized that higher fractions of toxic cyanobacteria in the diet of grazers would shift the balance towards a greater than linear, i.e. non-linear accumulation of MC in D. magna. This hypothesis w...

entomopathogenic fungi may be affected by pesticides used to protect crop plants. the in vitro compatibility of beauveria bassiana and metarhizium anisopliae with three fungicides and 16 insecticides was evaluated. the formulations of pesticides were tested in three concentrations (mean concentration (mc), half mc and twice the mc). all tested fungicides, at three concentrations, were incompati...

mesenchymal chondrosarcoma (mc) is an uncommon tumor with an aggressive behaviour. we present two cases of mc. the first one is a unique case of mc of the maxilla metastasized from the clavicle. the second describes mc in the mandible with extensive involvement of the condyle. a 31-year-old male and a 22-year-old male presented to saveetha dental college, with a 2-month history of progressive m...

Neurodegenerative disorders such as Parkinson’s disease, motor neuron disease and Alzheimer’s disease is characterized by loss of specific cells within certain regions of the brain. One of the most compelling questions is to determine why specific cell populations are vulnerable to neurodegeneration. We addressed this question by studying global gene expression changes using an animal model of ...

Neurodegenerative disorders such as Parkinson’s disease, motor neuron disease and Alzheimer’s disease is characterized by loss of specific cells within certain regions of the brain. One of the most compelling questions is to determine why specific cell populations are vulnerable to neurodegeneration. We addressed this question by studying global gene expression changes using an animal model of ...

An increase in mast cell (MC) numbers in hemopoietic tissues may be associated with (a) primary neoplastic MC disease (mastocytosis); (b) non-mast cell lineage myelogenous disorders (myelodysplastic or myeloproliferative syndromes and myeloid leukemias); or (c) reactive, i.e. non-clonal states (MC hyperplasia and reactive mastocytosis). However, the histologic discrimination between hyperplasti...

† We acknowledge the useful comments from Nerissa Brown, Woo-Jin Chan, Jeff Coulton, Neil Fargher, Sarah McVay, Gil Sadka, Andreas Simon and participants at the AFAANZ Annual Conference in 2005. This work was started by Andrew Lynch as part of his honour’s thesis at the University of Melbourne, and completed while Asher Curtis and Julian Yeo were PhD students at the University of New South Wale...