BACKGROUND Sudden infant death syndrome (SIDS) remains the leading cause of death among infants less than 1 year of age. Disturbed expression of some neurotransmitters and their receptors has been shown in the central nervous system of SIDS victims but no biological abnormality of the peripheral vago-cardiac system has been demonstrated to date. The present study aimed to seek vago-cardiac abno...

The association between Long QT syndrome (LQTS) and sudden infant death syndrome (SIDS) remains highly topical and even polarizing. Because the landmark Italian study of the QT interval and SIDS triggered extensive controversy, there has been a substantial and commendable effort to establish LQTS as one of the true causes of SIDS. The motivation underlying this effort is based on the fact that ...

Reported here are the proceedings of a symposium given in honor of Dr. Henry F. Krous upon his retirement as Clinical Professor of Pathology and Pediatrics at the University of California Schools of Medicine, and as Director of the San Diego SIDS/SUDC Research Project. Dr. Krous' distinguished 37-year-career was dedicated to research into sudden unexpected death in infancy and childhood, notabl...

BACKGROUND The neurobiology of social dysfunction in schizophrenia is unknown, but smell identification deficits (SIDs) exist in schizophrenia, and olfaction is related to social affiliation in other mammals. The SIDs have been linked with negative symptoms and the deficit syndrome, but any specificity of SIDs for social dysfunction is unstudied. Low intelligence might explain this relationship...

HISTORY: The SIDS Dossier and Testing Plan were reviewed at the 3rd SIDS Review Meeting where the following SIDS Testing Plan was agreed: no testing () testing (x) Testing on developmental toxicity/teratogenicity was underway at the time of the review meeting. The SIDS Initial Assessment Report was discusse d at SIAM 6 in 1997. It was recommended that the report should be re-drafted and present...

Sudden infant death syndrome (SIDS) is the sudden unexpected death of an apparently healthy infant younger than age 12 months whose cause of death remains unknown despite a thorough death scene investigation, a review of the clinical history, and an autopsy. Despite the huge achievement of the Back to Sleep program, SIDS remains one of the leading causes of infant death in the United States. In...

Sudden infant death syndrome (SIDS) is the leading cause of death among USA infants under 1 year of age accounting for ~2,700 deaths per year. Although formally SIDS dates back at least 2,000 years and was even mentioned in the Hebrew Bible (Kings 3:19), its etiology remains unexplained prompting the CDC to initiate a sudden unexpected infant death case registry in 2010. Due to their total depe...

Zusammenfassung Hintergrund Der plötzliche Kindstod (SIDS, „sudden infant death syndrome“) ist dank vieler Präventionsmaßnahmen heute deutlich seltener als noch vor ca. 30 Jahren. Wir führten einen schnellen systematischen Review zu effektiven Interventionsmaßnahmen durch und evaluierten ein mehrjähriges Präventionsprojekt in Hamm. Methodik Für den wurde eine systematische Recherche der Datenba...

BACKGROUND In this case-control study on sudden infant death syndrome (SIDS), the magnitude of the risk factors 'maternal smoking during pregnancy' and 'poor antenatal care' was assessed and the attributable proportions of SIDS incidence estimated. METHODS Perinatal data from 190 SIDS cases, who died between 1986 and 1990 at age > 7 days and had a diagnosis of SIDS confirmed by autopsy, were ...