OBJECTIVES This study sought to determine the clinical and biological significance of elevated cardiac troponin T (cTnT) in patients with neuromuscular diseases. BACKGROUND Practice guidelines regard cTnT and cardiac troponin I (cTnI) as equally sensitive and specific for the diagnosis of myocardial injury. Although cTnI is unique to myocardium, cTnT can be re-expressed in skeletal muscle in ...

Ontogenetic study on the expression of cytokeratin (CK) polypeptides within particular subsets of rat thymic epithelial cells (TEC) has been performed by a large panel of anti-CK monoclonal antibodies (mAbs) using the streptavidin-biotin immunoperoxidase method. Simultaneous presence of two or more CK subunits in the same TEC has been demonstrated by double immunofluorescence labeling. The obta...

OBJECTIVE The margin of a palatal cleft is a unique anatomical site since the palatal mucosa is continuous with the nasal or nasopharyngeal mucosa. The aim of this study was to compare the expression patterns of cytokeratins and basal membrane components of the mucosa in the area of the cleft. DESIGN Biopsies from the mucosa of the hard palate and from the cleft margin in the soft palate were...

background: human embryonic stem cells (hesc), which are derived from the inner cell mass of the blastocysts, have been considered to be pluripotent cells. in this study we examine the differentiating potential of hesc into hepatocytes by characterization of the expression of endoderm and liver-specific genes. methods: hesc were cultivated in suspension to form aggregates, the embryoid bodies. ...

context traumatic brain injury (tbi) is a leading cause of death, disability, and resource consumption per year. there are two kinds of brain injury in tbi, primary and secondary injuries. primary injury refers to the initial physical forces applied to the brain at the moment of impact. secondary injury occurs over a period of hours or days following the initial trauma and results from the acti...

A 65-year-old man in whom an inferior vena cava filter had been implanted for deep vein thrombosis was admitted to the cardiology department due to appetite loss and lumbago. Laboratory data showed increased total creatinine kinase (CK, 796 U/L, Picture 1, left) and CK-MB (1,213 U/ L), which exceeded the total CK value. Electrophoresis showed, in addition to an increase in CK-BB, a peak that mi...