Background: Sepsis in neonates presents itself with non-specific clinical features which makes early diagnosis difficult. However, procalcitonin (PCT) and other inflammatory markers have recently been considered as sensitive markers for the early detection of neonatal sepsis. Therefore, the present study aimed to determine the diagnostic value of PCT in the early detection of neonatal sepsis an...

Background Neonatal sepsis is one of the major causes of neonatal morbidity and mortality globally. Its incidence varies from 1 to 4 cases per 1,000 live births in developed countries. The burden of the problem occurs in the developing world while most confirmation is derived from developed countries. This study is aimed to assess the prevalence of neonatal sepsi...

sepsis is a significant health problem with an estimated 750,000 new cases in the usa annually. it is also the third leading cause of death in developed countries, equaling the number of fatalities from acute myocardial infarction. the high sepsis-related mortalities mean there is an urgent need to improve the diagnosis and management of sepsis patients. the aim of this study was the evaluation...

conclusions the results of this study indicated that patients with sepsis had lower serum vitamin d levels than healthy controls. also, patients with more severe disease had lower serum vitamin d levels, but to evaluate causation and determine whether vitamin d supplementation could be effective in reducing the risk or severity of sepsis, randomized controlled trials should be conducted. result...

Sepsis is the most common cause of neonatal mortality. As per National Neonatal-Perinatal Database (NNPD), 2002-2003, the incidence of neonatal sepsis in India was 30 per 1000 live births. Signs and symptoms of sepsis are nonspecific; therefore empirical antimicrobial therapy is promptly initiated after obtaining appropriate cultures. The early manifestations of neonatal sepsis are vague and il...

sepsis and septic shock are among mortality causes following major surgeries. the charlson co-morbidity index consists of 19 weighted categories related to chronic health which measures the burden of co-morbidity. the goal of this study was to determine the incidence of postoperative sepsis in patients underwent gynecological and gastrointestinal cancer surgeries and predictive role of charlson...

introduction: in a prospective study, we aimed to assess the value of enhanced rdw to predict sepsis and evaluate factors affecting length of icu stay and in-hospital mortality among sepsis patients. material and method: after exclusion of 27 patients, we included 160 adult patients with suspicious sepsis admitted at university affiliated hospital with 33 icu-beds from 2010 to 2012. nighty pati...

introduction early diagnosis of neonatal sepsis is essential for successful treatment. blood culture is a gold standard for diagnosis but the final results are not available until 48-72 hours after culture. interleukin-6 (il-6) as a marker plays a critical role in the induction of c-reactive protein (crp) synthesis in the liver. it has been hypothesized that this cytokine could be detected in b...