نتایج جستجو برای: سطح ldl

تعداد نتایج: 179584  

Journal: :The American journal of clinical nutrition 1996
G Schectman L E Boerboom J Hannah B V Howard R A Mueller A H Kissebah

To assess whether fish oil-induced alterations in low-density-lipoprotein (LDL) composition have distinct and important effects on LDL metabolism, we evaluated LDL kinetic behavior in cynomolgus macaques fed an atherogenic diet supplemented with either fish oil (1.6 g n-3 fatty acids; n = 10) or olive oil (n = 9) for > or = 6 mo. LDL from monkeys supplemented with fish oil or olive oil was isol...

Journal: :Arteriosclerosis and thrombosis : a journal of vascular biology 1991
H F Hoff J O'Neil

In this study we assessed whether low density lipoproteins (LDL) isolated from minced aortic atherosclerotic plaques obtained at autopsy (A-LDL) shared structural and functional properties with LDL oxidized by incubation with Cu2+ for 8-18 hours at 20 degrees C (Ox-LDL). Although both A-LDL and Ox-LDL represented monomeric particles about the size of LDL, both differed from LDL in that they sho...

Journal: :Journal of lipid research 1996
D Li S Devaraj C Fuller R Bucala I Jialal

Much data support a role for both low density lipoprotein (LDL) oxidation and glycation in atherogenesis. While alpha-tocopherol decreases the oxidative susceptibility of LDL, its role in decreasing LDL glycation is unclear. Hence we tested the effect of alpha-tocopherol both in vitro and in vivo on LDL oxidation and glycation. LDL was isolated after enrichment of plasma with alpha-tocopherol. ...

2013
Lawrence Baruch Valerie J. Chiong Sanjay Agarwal Bhanu Gupta

Objective. To determine if non-HDL cholesterol (N-HDL) and directly measured LDL cholesterol (D-LDL) are clinically equivalent measurements. Patients and Methods. Eighty-one subjects recruited for 2 cholesterol treatment studies had at least 1 complete fasting lipid panel and D-LDL performed simultaneously; 64 had a second assessment after 4 to 6 weeks, resulting in 145 triads of C-LDL, D-LDL, ...

Journal: :Circulation 2003
Sonia Benítez José Luis Sánchez-Quesada Vicent Ribas Oscar Jorba Francisco Blanco-Vaca Francesc González-Sastre Jordi Ordóñez-Llanos

BACKGROUND Electronegative LDL [LDL(-)], a modified subfraction of LDL present in plasma, induces the release of interleukin-8 and monocyte chemotactic protein-1 from cultured endothelial cells. METHODS AND RESULTS We demonstrate that platelet-activating factor acetylhydrolase (PAF-AH) is mainly associated with LDL(-). LDL(-) had 5-fold higher PAF-AH activity than the nonelectronegative LDL s...

Journal: :The Journal of biological chemistry 1989
C P Sparrow S Parthasarathy D Steinberg

The formation of cholesterol-loaded macrophage foam cells in arterial tissue may occur by the uptake of modified lipoproteins via the scavenger receptor pathway. The macrophage scavenger receptor, also called the acetylated low density lipoprotein (Ac-LDL) receptor, has been reported to recognize Ac-LDL as well as oxidized LDL species such as endothelial cell-modified LDL (EC-LDL). We now repor...

Journal: :Physical chemistry chemical physics : PCCP 2015
Hitoshi Kusama Kazuhiro Sayama

The intermolecular interactions of the two most basic Ru(II) complex dyes for dye-sensitized solar cells (DSSCs), N719 and N749, with the iodine species are investigated using density functional theory (DFT). In addition to interactions with a single I2 molecule, multiple I2 interactions and simultaneous interactions of I2 and I(-) occur. N719 with two isothiocyanato (NCS) ligands interacts wit...

Journal: :Atherosclerosis 2021

Controversy over fat quality and cardiovascular disease risk stems from a series of meta-analyses prospective cohort randomised intervention trials, which found little evidence for significant relationship between the intake saturated endpoints. Possible explanations these null findings include difficulties inherent in estimating true food intake, confounding effects macronutrient replacement c...

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