Resíduos hortícolas podem ser utilizados para a cultivo de cogumelos e obtenção proteases. O objetivo desta pesquisa foi avaliar o potencial resíduos lignocelulósicos como substratos crescimento micelial produção proteases por Lentinus crinitus DPUA 1693. A cultura matriz preparada em ágar batata dextrose (BDA) suplementada com extrato levedura (YE) 0,5% (p/v). vertical (VMC) realizado tubos en...

Every discrete group with Kazhdan’s Property (T) (resp. Property (FA)) is a quotient of a torsion-free, word hyperbolic group with Property (T) (resp. (FA)). Recall ([HV], [Ser]) that a countable discrete group G has Property (T) (resp. (FA)) if every isometric action of G on an affine Hilbert space (resp. on a simplicial tree) has a fixed point (or, equivalently, has bounded orbits). As immedi...

We hypothesized that the genomic response to folate deficiency might be different between breast cancer cases and healthy subjects. To test this hypothesis, we performed a comprehensive study on the genotoxic and cytotoxic effects of in vitro folic acid (FA) deficiency on primary human lymphocytes from 19 breast cancer patients and 20 age-matched healthy females from Yunnan, China using the cyt...

Afforestation plays an important role in soil protection and ecological restoration. The objective of this study is to understand the effect of afforestation on soil carbon and soil microbial communities in the Loess Plateau of China. We measured two chemically-separated carbon fractions (i.e., humic acid, HA, and fulvic acid, FA) and soil microbial communities within shrublands (18-year-old Ca...

This study tests the hypothesis that the metabolic and endocrine shift characterizing the phase II-phase III transition during prolonged fasting is related to a decrease in fatty acid (FA) oxidation. Changes in plasma concentrations of various metabolites and hormones and in lipolytic fluxes, as determined by continuous infusion of [2-(3)H]glycerol and [1-(14)C]palmitate, were examined in vivo ...

Introduction: Recent developments have enabled automated voxel-based statistical (VBS) analyses of DTI data, so that fractional anisotropy (FA) images, for example, may be quantitatively compared between groups of subjects without manual investigator dependency. In contrast to conventional VBM of T1w images, spatial normalization for VBS of FA images (FA-VBS) may be based on different image con...

BACKGROUND Chronotherapy with antineoplastic drugs is a rather new strategy of reducing cytotoxic side effects. Because the circadian timing of 5-fluorouracil (5-FU) was reported to result in a higher efficacy and lower toxicity, the authors conducted a chronopharmacologic Phase I trial with 5-FU and folinic acid (FA). METHODS Eight patients with advanced colorectal cancer received 5-FU (init...

BACKGROUND The important metastatic potential of lung cancers is directly correlated with cell adhesion. Cell-extracellular matrix interactions occur in specialized structures termed focal adhesion (FA) complexes. Our aims were to investigate: (i) the expression of the major FA components in three lung cancer cell lines (non metastatic: A549, or metastatic: Calu-1 and H460), (ii) the modificati...

Nitro-fatty acids (NO2-FA) are metabolic and inflammatory-derived electrophiles that mediate pleiotropic signaling actions. It was hypothesized that NO2-FA would impact mitochondrial redox reactions to induce tissue-protective metabolic shifts in cells. Nitro-oleic acid (OA-NO2) reversibly inhibited complex II-linked respiration in isolated rat heart mitochondria in a pH-dependent manner and su...