The high osmolarity glycerol (HOG) signalling system in yeast belongs to the class of Mitogen Activated Protein Kinase (MAPK) pathways that are found in all eukaryotic organisms. It includes at least three scaffold proteins that form complexes, and involves reactions that are strictly dependent on the set of species bound to a certain complex. The scaffold proteins lead to a combinatorial incre...

Pedestrian detection is the key technology in Advanced Driver Assistant System (ADAS).Until recently, pedestrian detection, which is realized as the vehicle equipment, still doesn't have the mature product. So, this thesis proposes a novel pedestrian detection system on board with the E-HOG (Histogram of Gradient) IP (intellectual property), can be used as the real time vehicle equipment. Three...

The high-osmolarity glycerol (HOG) mitogen-activated protein (MAP) kinase pathway mediates adaptation to high-osmolarity stress in the yeast Saccharomyces cerevisiae. Here we investigate the function of HOG in the human opportunistic fungal pathogen Candida glabrata. C. glabrata sho1Delta (Cgsho1Delta) deletion strains from the sequenced ATCC 2001 strain display severe growth defects under hype...

Road traffic signs provide instructions, warning information, to regulate driver behavior. In addition, these signs provide a reliable guarantee for safe and convenient driving. The Traffic Sign Detection and Recognition (TSDR) system is one of the primary applications for Advanced Driver Assistance Systems (ADAS). TSDR has obtained a great deal of attention over the recent years. But, it is st...

Background and objective Intensive livestock farming in Germany is characterized by two facts. First, the production seems hardly to respond to the considerable price changes that occurred during the past decades. Second, the spatial allocation of production is rather unequal, though no special natural conditions are required for this business. Such an unequal distribution is not desired by agr...

Face identification under small sample conditions is currently an active research area. In a case of very few reference samples, optimally exploiting the training data to make a model which has a low generalization error is an important challenge to create a robust face identification algorithm. In this paper we propose to combine the histogram of oriented gradients (HOG) and the bag of words (...

The HoG descriptor has become one of the most popular low-level image representations in computer vision: even a small improvement in its ability to represent images would be useful. In this project, we explore several ways to enhance HoG at minimal performance cost. One approach is to separate high-frequency gradients (‘step edges’), which tend to represent edges, from lowfrequency gradients (...

In Saccharomyces cerevisiae, the mating, filamentous growth (FG), and high-osmolarity glycerol (HOG) mitogen-activated protein kinase (MAPK) signaling pathways share components and yet mediate distinct responses to different extracellular signals. Cross talk is suppressed between the mating and FG pathways because mating signaling induces the destruction of the FG transcription factor Tec1. We ...

OBJECTIVE The oxidation of LDLs is considered a key step in the development of atherosclerosis. How LDL oxidation contributes to atherosclerosis remains poorly defined. Here we report that oxidized and glycated LDL (HOG-LDL) causes aberrant endoplasmic reticulum (ER) stress and that the AMP-activated protein kinase (AMPK) suppressed HOG-LDL-triggered ER stress in vivo. RESEARCH DESIGN AND MET...

Adaptation is an important property of living organisms enabling them to cope with environmental stress and maintaining homeostasis. Adaptation is mediated by signaling pathways responding to different stimuli. Those signaling pathways might communicate in order to orchestrate the cellular response to multiple simultaneous stimuli, a phenomenon called crosstalk. Here, we investigate possible me...