This paper introduces a special issue of Cognitive Science initiated on the 25th anniversary of the publication of Parallel Distributed Processing (PDP), a two-volume work that introduced the use of neural network models as vehicles for understanding cognition. The collection surveys the core commitments of the PDP framework, the key issues the framework has addressed, and the debates the frame...

Network virtualization provides the ability to run multiple concurrent virtual networks over a shared substrate. However, it is challenging to design such a platform to host multiple heterogenous and often highly customized virtual networks. Not only high degree of flexibility is desired for virtual networks to customize their functions, fast packet forwarding is also required. This paper prese...

The insulin/IGF-1 signaling (IIS) pathway is a conserved regulator of longevity, development, and metabolism. In Caenorhabditis elegans IIS involves activation of DAF-2 (insulin/IGF-1 receptor tyrosine kinase), AGE-1 (PI 3-kinase), and additional downstream serine/threonine kinases that ultimately phosphorylate and negatively regulate the single FOXO transcription factor homolog DAF-16. Phospha...

This paper presents the extraction of a legal access control policy and a conflict resolution policy from the EU Data Protection Directive [1]. These policies are installed in a multi-policy authorization infrastructure described in [2, 3]. A Legal Policy Decision Point (PDP) is constructed with a legal access control policy to provide automated decisions based on the relevant legal provisions....

BACKGROUND Symptomatology and physiology differ between men and women and across the menstrual cycle in irritable bowel syndrome (IBS). Ovarian hormones influence 5-hydroxytryptamine (5-HT), an amine known to play a role in gut motor-sensory function. AIM To assess the effects of gender and menstrual status on platelet-depleted plasma (PDP) 5-HT concentration in IBS patients with diarrhoea (I...

The pick-up and delivery problem (PDP) consists in finding a set of optimal routes for a fleet of vehicles respecting the precedence and pairing constraints and visiting all transportation requests. The transport of personnel on oil platforms is a real application of PDP which we are interested in. The problem is modeled as a set covering problem that is solved via a column generation technique...

The PDP(Partial Dominant Pruning) method is known as most practical method to reduce overlapped broadcasting messages by designating forward node as in-fly type when broadcasting occurs in the mobile wireless network with directional antenna. In this paper, we introduce DPDP(Directional PDP) that reduces not only number of nodes but number of used antenna elements simultaneously. By simulation,...

The Pickup and Delivery Problem (PDP) consists in defining a set of routes that satisfy transportation requests between a pickup point and a delivery point. This paper addresses a variant of the PDP where the requests are transportation demands arising from disabled persons. Vehicle passengers can change of vehicle during their trip on specific locations called “transfer points”. Solving this v...

PURPOSE OF REVIEW We discuss features of Parkinson's disease psychosis (PDP) including symptomology and pathophysiology. Treatment options, including non-pharmacologic strategies, dose reduction of offending agents, and the addition of non-dopaminergic antipsychotics, are addressed. The efficacy of second-generation antipsychotics and novel agents is examined. RECENT FINDINGS Pimavanserin, a ...

Programming is an activity centred primarily around the keyboard which is not necessarily the optimal input device for all users. Little research has taken place into alternative input devices for programming despite huge advances in handwriting and voice recognition for natural language. This project explored using a pen as the primary input device for programming. A variety of different metho...