BACKGROUND Tuberculosis (TB) caused by Mycobacterium tuberculosis is one of the leading causes of death from infectious diseases worldwide. Sputum smear microscopy remains the most widely available pulmonary TB diagnostic tool particularly in resource limited settings. A highly sensitive diagnostic with minimal infrastructure, cost and training is required. Hence, we assessed the diagnostic per...

A técnica de Loop Mediated Isothermal Amplification Assay (LAMP) amplamente difundida a partir dos anos 2000, baseia-se na utilização primers sensíveis e específicos da BST DNA polimerase junto à outros reagentes para amplificação uma sequência alvo sob temperatura constante. Durante LAMP ocorrem sucessivos ciclos etapa não cíclica produção exponencial amplicons comprimentos variáveis. Esses pr...

Lysosomal membrane protein 2 (LAMP-2) is a target of antineutrophil cytoplasmic autoantibodies (ANCA) in addition to the more commonly known targets proteinase 3 and myeloperoxidase. The prevalence of anti-LAMP-2 antibodies and their relationship to disease in ANCA glomerulonephritis are not well described. We measured anti-LAMP-2 reactivity in 680 sera samples (two academic centers) from patie...

Ultraviolet germicidal irradiation (UVGI) uses UVC radiation produced by low pressure Hg vapor lamps to control biological air contaminants. Lamp UV output depends on multiple factors, including accumulated operating time (age) and the thermal effects of ambient air temperature and velocity. Additionally, the life of some lamp types depends on the frequency of on-off cycles. Models of lamp life...

1 Abstract A compact visual representation, called the 3D Layered, Adaptive-resolution and Multi-perspective Panorama (LAMP), is proposed for representing large-scale 3D scenes with large variations of depths and obvious occlusions. Two kinds of 3D LAMP representations are proposed: the relief-like LAMP and the image-based LAMP. Both types of LAMPs concisely represent almost all the information...

نخستین گام در راستای تحلیل و ارزیابی ریسک‌های زنجیره تأمین شناسایی این ریسک‌ها است. روش‌های مرسوم بر اساس فیلترهای دستی یا خودکار داده‌­محور ارائه شده فیلتر به‌­دلیل محدودیت‌های نمونه‌گیری دارای مشکلات اعتبارسنجی هستند از طرف دیگر مبتنی داده، داده‌های ریسک که پیچیده مبهم هستند، عملکرد ضعیفی دارند. برای پرکرده خلل پژوهشی، پژوهش، چارچوبی تعاملی بین تحلیل‌­گر ماشین حجم وسیعی حوزه مواد غذایی با است...

Lysosomal/phagosomal membranes of mammalian cells are coated by highly conserved glycoproteins (lamps) that are thought to protect the membranes from degradation. Interestingly, we identified an amino acid sequence in human lamp-1 characteristic of a cleavage site for the Neisseria gonorrhoeae IgA1 protease. Furthermore, gonococci are detected in h-lamp-1-positive vacuoles after their uptake by...