Comparison of human sequences with the DNA of other mammals is an excellent means of identifying functional elements in the human genome. Here we describe the utility of high-density oligonucleotide arrays as a rapid approach for comparing human sequences with the DNA of multiple species whose sequences are not presently available. High-density arrays representing approximately 22.5 Mb of nonre...

The transition to digital in the TV broadcasting industry is already gradually being performed while the complete digital switchover seems now possible to be accomplished within the near future. This article describes and analyses this phenomenon and the role of MPEG-21 may play in it. MPEG-21 is the ISO/IEC standard currently under development in MPEG (ISO/IEC JTC1/SC29/WG11). Unlike preceding...

The visual system adapts to its environment. Some adaptive changes are detrimental-perception is no longer veridical. Others are beneficial-the ability to discriminate two stimuli improves. The latter may reflect the visual system's ability to zoom-in on the currently relevant properties of the environment. We studied the neural basis of adaptive changes in the middle temporal area (MT) of maca...

An immensely influential paper in the history of the study of chaos was the work of Ruelle and Takens [1], later extended with Newhouse [2] on the robustness of quasiperiodic dynamics with 3 or more incommensurate frequencies. This addressed the question of whether complexity in dynamics was likely to occur through the accumulation of Hopf-like bifurcations adding additional frequencies (and pr...

The use of radiotherapy and or chemotherapy can result in a wide range of acute and chronic side effects. These are generic concerns for cancer treatment in general. Side effects include bone marrow suppression, and cardiac and lung damage. A full discussion is beyond the scope of this document. These guidelines deal with complications that are of greater significance in younger patients with l...