Electrospray ionization (ESI) is widely used in liquid chromatography coupled to mass spectrometry (LC-MS) for the analysis of biomolecules. However, the ESI process is still not completely understood, and it is often a matter of trial and error to enhance ESI efficiency and, hence, the response of a given set of compounds. In this work we performed a systematic study of the ESI response of 14 ...

BACKGROUND No studies to date have compared bone mineral density (BMD) changes after epidural steroid injection (ESI) between postmenopausal patients taking antiosteoporotic medication and those who are not. OBJECTIVE The aim of the present study was to analyze the relationship between ESI and BMD changes in postmenopausal patients according to antiosteoporotic medication use. STUDY DESIGN ...

STUDY DESIGN Retrospective analysis of data from patients participating in the Lumbar Spinal Stenosis Outcome Study (LSOS). OBJECTIVE The aim of LSOS was to assess clinical outcomes after surgical or nonoperative treatment in patients with and without prior epidural steroid injections. SUMMARY OF BACKGROUND DATA Epidural steroid injections (ESI), a common treatment modality, reduce symptoms...

BACKGROUND AND PURPOSE The aim of this study was to determine the usefulness of three-dimensional (3D) scalp EEG source imaging (ESI) in partial epilepsy in comparison with the results of presurgical evaluation, magnetoencephalography (MEG), and electrocorticography (ECoG). METHODS The epilepsy syndrome of 27 partial epilepsy patients was determined by presurgical evaluations. EEG recordings ...

Objective To evaluate the incidence, types and association of systemic reactions after an epidural steroid injection (ESI) with patient demographics, ESI factors and repeated occurrence of an ESI. Materials and Methods This prospective observational study was approved by the Institutional Review Board of our hospital, and written informed consent was obtained from all the participants. From O...

Six synthesized 6-nitroquipazine derivatives were examined by electron ionization (EI) and electrospray ionization (ESI) mass spectrometry in positive and negative ion mode. The compounds exhibit high affinity for the serotonin transporter (SERT) and belong to a new class of SERT inhibitors. The EI mass spectra registered in negative ion mode showed prominent molecular ions for all the compound...

A rapid method for the characterization of sake by measuring the ratio of the peak intensities of taste components in sake, using electrospray ionization/mass spectrometry (ESI/MS) has been developed. Twenty-six different kinds of sake samples were collected and analyzed by ESI/MS. The ESI/MS ion peaks were assigned to amino acids, organic acids, and sugars. Principal component analysis was per...

BACKGROUND Microbial secondary metabolism is regulated by a complex and mostly-unknown network of global and pathway-specific regulators. A dozen biosynthetic gene clusters for secondary metabolites have been reported in myxobacteria, but a few regulation factors have been identified. RESULTS We identified a transcription regulator Esi for the biosynthesis of epothilones. Inactivation of esi ...

To alleviate environmental pollution and improve the energy usage efficiency of terminals, energy systems integration (ESI) has become an important paradigm in the energy structure evolution. Power, gas and heat systems are becoming tightly interlinked with each other in ESI. The dispatching strategy of local-area ESI has significant impact on its operation. In this paper, a local-area ESI oper...