نتایج جستجو برای: ترمولیز آنالیز ترموگراویمتری atg با ترموبلانس

تعداد نتایج: 673199  

Journal: :Blood 2015
Laurent Pascal Luciana Tucunduva Annalisa Ruggeri Didier Blaise Patrice Ceballos Patrice Chevallier Jan Cornelissen Natacha Maillard Reza Tabrizi Eefke Petersen Werner Linkesch Henrik Sengeloev Chantal Kenzey Antonio Pagliuca Ernst Holler Hermann Einsele Eliane Gluckman Vanderson Rocha Ibrahim Yakoub-Agha

We analyzed 661 adult patients who underwent single-unit (n = 226) or double-unit (n = 435) unrelated cord blood transplantation (UCBT) following a reduced-intensity conditioning (RIC) consisting of low-dose total body irradiation (TBI), cyclophosphamide, and fludarabine (Cy/Flu/TBI200). Eighty-two patients received rabbit antithymocyte globulin (ATG) as part of the conditioning regimen (ATG gr...

2015
Stephanie A. Wolanin Jeffrey G. Demain Eric A. Meier

Antithymocyte globulin (ATG) is a polyclonal gamma immunoglobulin derived from either rabbit or equine serum that serves as therapy for aplastic anemia; however, ATG causes serum sickness in up to 70% and anaphylaxis in up to 5% of recipients. Intradermal (ID) skin testing has been the primary technique used to evaluate for a preexisting Gell and Coombs type I hypersensitivity reaction to ATG. ...

Journal: :Annals of transplantation 2008
Min Jeong Kim Dimitrios Tsinalis Stefan Franz Isabelle Binet Lorenz Gürke Michael J Mihatsch Jürg Steiger Gilbert Thiel Michael Dickenmann

BACKGROUND Despite all the advantages in the immunosuppressive therapy, kidney transplantation in immunologically high risk patients remains a challenge. Ideally, an induction therapy should provide maximal graft protection, while adverse events rate and costs remain as low as possible. MATERIAL & METHODS Immunologically high risk kidney recipients with CDC-PRA ł 25% within the last 3 years, ...

Journal: :Blood 1985
P Gascon N C Zoumbos G Scala J Y Djeu J G Moore N S Young

Anti-thymocyte globulin (ATG) provides effective therapy for many patients with aplastic anemia, and its mechanism of action has been presumed to be secondary to lymphocytotoxicity. However, our studies of lymphocyte function in aplastic anemia show marked abnormalities of lymphokine production, which ATG may modulate. In 12 of 17 patients with aplastic anemia, interleukin 2 (IL2) production wa...

Journal: :Cancer research 1990
T J Panella A T Huang

Anti-thymocyte globulin (ATG), a horse antiserum to human thymus tissue, has been shown to induce granulocytic differentiation of the HL-60 human leukemia cell line. In this paper we describe the effect of ATG on leukemic blasts and its effect on other human leukemia cell lines in vitro. The in vitro differentiation effect of ATG was observed in blasts from two patients with leukemia and the hu...

Journal: :Against the Grain 2018

Journal: :Critical reviews in oncology/hematology 2013
Sebastian Theurich Hans Fischmann Geothy Chakupurakal Alexander Shimabukuro-Vornhagen Jens M Chemnitz Udo Holtick Achim Rothe Christof Scheid Michael Hallek Nicole Skoetz Michael von Bergwelt-Baildon

BACKGROUND Despite advances made in allogeneic hematopoietic stem cell transplantation (alloSCT), graft versus host disease (GvHD) remains a major problem. The main strategy to combat GvHD is prophylaxis and ATG plays a major role in this arena. Conflicting reports on the effectiveness of ATG on GvHD prevention prompted us to address this question by means of a systematic review and meta-analys...

2015
Laura Laprell Emilienne Repak Vilius Franckevicius Felix Hartrampf Jan Terhag Michael Hollmann Martin Sumser Nelson Rebola David A. DiGregorio Dirk Trauner

N-methyl-D-aspartate receptors (NMDARs) play a central role in synaptic plasticity, learning and memory, and are implicated in various neuronal disorders. We synthesized a diffusible photochromic glutamate analogue, azobenzene-triazole-glutamate (ATG), which is specific for NMDARs and functions as a photoswitchable agonist. ATG is inactive in its dark-adapted trans-isoform, but can be converted...

2015
Frédéric Baron Pierre Zachée Johan Maertens Tessa Kerre Aurélie Ory Laurence Seidel Carlos Graux Philippe Lewalle Michel Van Gelder Koen Theunissen Evelyne Willems Marie-Paule Emonds Ann De Becker Yves Beguin

BACKGROUND Few studies thus far have compared head-to-head different non-myelooablative conditioning regimens for allogeneic hematopoietic cell transplantation (allo-HCT). METHODS Here, we report the results of a phase II multicenter randomized study comparing non-myeloablative allo-HCT from HLA-identical siblings (n = 54) or from 10/10 HLA-matched unrelated donors (n = 40) with either fludar...

Journal: :Molecular and cellular biology 1995
D F Yun F Sherman

The steady-state levels and half-lives of CYC1 mRNAs were estimated in a series of mutant strains of Saccharomyces cerevisiae containing (i) TAA nonsense codons, (ii) ATG initiator codons, or (iii) the sequence ATA ATG ACT TAA (denoted ATG-TAA) at various positions along the CYC1 gene, which encodes iso-1-cytochrome c. These mutational alterations were made in backgrounds lacking all internal i...

نمودار تعداد نتایج جستجو در هر سال

با کلیک روی نمودار نتایج را به سال انتشار فیلتر کنید