The binding of the Ku protein to DNA was investigated using the atomic force microscope@Ku was found to bind predominantly to the ends of double-stranded DNA. Experiments with plasmid DNA revealed that Ku does not bind to circular plasmids but does bind to plasmids that have been linearized by treatment with ionizing radiation. The binding ofKu to poly(dG-dC)poly(dG-dC) polynucleotides and to a...

Precision and Intelligence Laboratory, Tokyo Institute of Technology, 4259 Nagatsuta-cho, Midori-ku, Yokohama 226-8503, Japan 1Interdisciplinary Graduate School of Science and Engineering, Tokyo Institute of Technology, 4259 Nagatsuta-cho, Midori-ku, Yokohama 226-8503, Japan 2Division of Research and Development, MedTech Heart Inc., 3-24-8 Asakusabashi, Taito-ku, Tokyo 111-0053, Japan 3School o...

1 Systems Biology Group, Kitano Symbiotic Systems Project, ERATO, JST, M31 6A, 6-31-15, Jingu-Mae, Shibuya-ku, Tokyo 150-0001, Japan 2 Department of Information Science, Graduate School of Science, University of Tokyo, 7-3-1, Hongo, Bunkyo-ku, Tokyo, 113-0034, Japan 3 Human Genome Center, Institute of Medical Science, University of Tokyo, 4-6-1 Shirokanedai, Minato-ku, Tokyo, 108-8639, Japan 4 ...

From the $Department of Biology, Faculty of Science, Ochanomizu University, Bunkyo-ku, Tokyo 112, the §Department of Physiological Chemistry and Nutrition, Faculty of Medicine, **Department of Biophysics and Biochemistry, Faculty of Science, Uniuersity of Tokyo, Bunkyo-ku, Tokyo 113, the TTokyo Metropolitan Institute of Gerontology, Itabashi-ku, Tokyo 173, and the IlResearch Institute for Disea...

Department of Microbiology' and Department of Laboratory Animal Science,5 Tokyo Metropolitan Institute of Medical Science, Honkomagome, Bunkyo-ku, Tokyo 113, Department of Pathology, National Institute of Health, Toyama, Shinjuku-ku, Tokyo 162,3 Japan Poliomyelitis Research Institute, Higashimurayama, Tokyo 189,2 Central Institlite for Experimental Animals, Nogawa, Miyamae-ku, Kawasaki, Kanagaw...

Takahiro Sagawa and Masahito Ueda 1 The Hakubi Center, Kyoto University, Yoshida-ushinomiya cho, Sakyo-ku, Kyoto 606-8302, Japan 2 Yukawa Institute for Theoretical Physics, Kyoto University, Kitashirakawa-oiwake cho, Sakyo-ku, Kyoto 606-8502, Japan Department of Physics, University of Tokyo, 7-3-1, Hongo, Bunkyo-ku, Tokyo, 113-8654, Japan ERATO Macroscopic Quantum Control Project, JST, 2-11-16 ...

S. Toyoda, H. Kumigashira, M. Oshima, G. L. Liu, Z. Liu, and K. Ikeda Department of Applied Chemistry, The University of Tokyo, Bunkyo-ku, Tokyo 113-8656, Japan Core Research for Evolutional Science and Technology, JST, Bunkyo-ku, Tokyo, 113-8656, Japan Univ-of-Tokyo Synchrotron Radiation Research Organization, Bunkyo-ku, Tokyo 113-8656, Japan Semiconductor Technology Academic Research Center, ...

Department of Chest Surgery, Kyushu Cancer Center, Notame 595, Minami-ku, Fukuoka 8 15 (K. V., H. M., E. V., N. N., H. U., N. H., M. 0.); Department of Immunology, Cancer Research Institute, Kyushu University Medical School, Maidashi 3-1-1 , Higashi-ku, Fukuoka 8 12 (K. N.); Institute of Immunological Science, Hokkaido University, Kita-ku, Sapporo 060 (I. A.]; and The Third Department of Intern...

Division of Food Science and Biotechnology, Graduate School of Agriculture, Kyoto University, Kitashirakawa Oiwake-cho, Sakyo-ku, Kyoto 606-8502, Japan, Department of Chemistry, Graduate School of Science, Kyoto University, Kitashirakawa Oiwake-cho, Sakyo-ku, Kyoto 606-8502, Japan, Division of Integrated Life Science, Graduate School of Biostudies, Kyoto University, Kitashirakawa Oiwake-cho, Sa...

From Cellular and Structural Physiology Institute (CeSPI), Nagoya University, Furo-cho, Chikusa-ku, Nagoya 464-8601, Japan Department of Basic Medical Science, Graduate School of Pharmaceutical Sciences, Nagoya University, Furo-cho, Chikusa-ku, Nagoya 464-8601, Japan Department of Biophysics, Graduate School of Science, Kyoto University, Oiwake, Kitashirakawa, Sakyo-ku, Kyoto 606-8502, Japan Bi...