The partition coefficients (Kps) of six anti-inflammatory steroid drugs, dexamethasone (DMS), betamethasone (BMS), triamcinolone acetonide (TCLA), fluocinolone acetonide (FCLA), betamethasone 17,21-dipropionate (BMSDP), and clobetasole propionate (CBSP), for phosphatidylcholine (PC), and PC-cholesterol small unilamellar vesicles (SUVs) were determined by a second-derivative spectrophotometric m...

Degradation of the essential amino acid tryptophan along the kynurenine pathway (KP) yields several neuroactive intermediates, including the free radical generator 3-hydroxykynurenine, the excitotoxic N-methyl-D-aspartate (NMDA) receptor agonist quinolinic acid, and the NMDA and 7 nicotinic acetylcholine receptor antagonist kynurenic acid. The ambient levels of these compounds are determined by...

Using the determinant representation of gauge transformation operator, we have shown that the general form of τ function of the q-KP hierarchy is a q-deformed generalized Wronskian, which includes the q-deformed Wronskian as a special case. On the basis of these, we study the q-deformed constrained KP (q-cKP) hierarchy, i.e. l-constraints of q-KP hierarchy. Similar to the ordinary constrained K...

The kynurenine pathway (KP) is a major degradative pathway of tryptophan ultimately leading to the production of nicotinamide adenine dinucleotide (NAD(+)) and is also one of the major regulatory mechanisms of the immune response. The KP is known to be involved in several neuroinflammatory disorders including Alzheimer's disease, amyotrophic lateral sclerosis, AIDS dementia complex, Parkinson's...

introduction: kisspeptin-13 (kp-13) is a novel endogenous factor, increases synaptic transmission and is involved in several behavioral functions such as anxiety, locomotion, epilepsy and avoidance learning. however, the role of this peptide on cognition has not been well clarified yet. here we studied the effect of kisspeptin-13 pretreatment on spatial learning and also interaction with cholin...

BACKGROUND AND PURPOSE It has not been clarified whether the postoperative resolution of vertebral deformities achieved by KP are superior to those achieved by VP. We compared the outcomes of KP and VP, taking into account the presence of vertebral mobility, to determine whether the balloon inflation in KP may contribute to postoperative resolution of the vertebral deformities in patients with ...

The kynurenine pathway (KP) is the major metabolic pathway of the essential amino acid tryptophan (TRP). Stimulation by inflammatory molecules, such as interferon-γ (IFN-γ), is the trigger for induction of the KP, driving a complex cascade of production of both neuroprotective and neurotoxic metabolites, and in turn, regulation of the immune response and responses of brain cells to the KP metab...

P elements inserted in the Telomere Associated Sequences (TAS) at the left end of the X chromosome are determiners of cytotype regulation of the entire P family of transposons. This regulation is mediated by Piwi-interacting (pi) RNAs derived from the telomeric P elements (TPs). Because these piRNAs are transmitted maternally, cytotype regulation is manifested as a maternal effect of the TPs. W...

We propose a hamiltonian formulation of the N = 2 supersymmetric KP type hierarchy recently studied by Krivonos and Sorin. We obtain a quadratic hamiltonian structure which allows for several reductions of the KP type hierarchy. In particular , the third family of N = 2 KdV hierarchies is recovered. We also give an easy construction of Wronskian solutions of the KP and KdV type equations.

This study aims to develop and validate an investigator global assessment score (IGA) for keratosis pilaris (KP), a highly prevalent, benign, follicular disorder, standardize disease assessment. To our knowledge, there is currently no scoring system KP. A composite IGA score, Keratosis Pilaris Area Index (KPAI), was created compared 0-4 defined KP known as KP-IGA. validation done determine the ...