Animals can move in not only elegant but also energy efficient ways. Their skin is one of the key components for this achievement. It provides a proper friction for forward motion and can protect them from slipping on a surface during locomotion. Inspired by this, we applied real shark skin to the foot soles of our hexapod robot AMOS. The material is formed to cover each foot of AMOS. Due to sh...

Emerging mobile and ubiquitous computing environments present hard challenges to software engineering. The use of mobile code has been suggested as a natural fit for simplifying software development for these environments. Existing strategies for locating mobile code assume an underlying fixed, stable network. An alternative approach is required for mobile environments, where network size and r...

Amos Golan Department of Economics, American University, Roper 200, 4400 Massachusetts Ave., NW, Washington, DC 20016, USA.

Anti-miRNA antisense inhibitors (AMOs) have demonstrated their utility in miRNA research and potential in miRNA therapy. Here we report a modified AMO approach in which multiple antisense units are engineered into a single unit that is able to simultaneously silence multiple-target miRNAs, the multiple-target AMO or MTg-AMO. We validated the technique with two separate MTg-AMOs: anti-miR-21/ant...

MicroRNAs (miRNAs) are small noncoding RNAs that regulate gene expression post-transcriptionally. Previous studies, which characterized miRNA function, revealed their involvement in fundamental biological processes. Importantly, miRNA expression is deregulated in many human diseases. Specific inhibition of miRNAs using chemically modified anti-miRNA oligonucleotides (AMOs) can be a potential th...

Information becomes a more and more valuable asset in today’s organizations. Therefore the need of creating an integrated view over all available data sources arises. Several technical problems must be overcome in the design and implementation of a system for integrating different data sources. To the main obstacles count autonomy, data heterogeneity and different query capabilities of the repo...