نتایج جستجو برای: اپیگالوکاتچین گالات egcg
تعداد نتایج: 1826 فیلتر نتایج به سال:
(-)-Epigallocatechin gallate (EGCG) and (-)-epigallocatechin (EGC) are major green tea catechins with antioxidant and anticancer activities. In this study, we characterized the glucuronidation of EGCG and EGC in human, mouse, and rat microsomes and by nine different human UGT 1A and 2B isozymes expressed in insect cells. Six EGCG and EGC glucuronides were biosynthesized, and their structures we...
Nitric oxide (NO) plays an important role in inflammation and multiple stages of carcinogenesis. We investigated the effect of various tea polyphenols and caffeine on the induction of NO synthase (NOS) in thioglycollate-elicited and lipopolysaccharide (LPS)-activated peritoneal macrophages. Gallic acid (GA), (2)-epigallocatechin (EGC), and (2)-epigallocatechin-3-gallate (EGCG), the major tea ca...
The anti-oxidant effects of epigallocatechin gallate (EGCG) and alpha lipoic acid (ALA) have been demonstrated in previous studies. The kidney protection effects of EGCG and ALA in patients with kidney injury are still under investigation. The purpose of this study is to investigate the anti-inflammatory and anti-oxidant effects of EGCG and ALA on high glucose-induced human kidney cell damage. ...
Catechin (epicatechin (EC), epicatechin gallate (ECg), epigallocatechin (EGC) and epigallocatechin gallate (EGCg)), which occur in green tea and black tea, possess strong bactericidal action. We observed a reactive oxygen species that was generated from the catechins as the active mechanism: and this reactive oxygen was identified. EGCg reacted with the dissolved oxygen in aqueous solution, res...
تأثیر مکمل اپی گالو کاتچین گالات بر مقیاس اندازه گیری کمای گلاسکو در بیماران با آسیب مغزی پس از ضربه
مقدمه: آسیب مغزی پس از ضربه علت عمدۀ مرگ و ناتوانی در افراد جوان می باشد. مکمل اپی گالو کاتچین گالات چای سبز به طور مطلوب بسیاری از فرایندهای اشاره شده در خونریزی ثانویه آسیب مغزی شامل: التهاب عصبی و آسیب های آنتی اکسیدانی در حیوانات مورد مطالعه را تحت تأثیر قرار می دهد. در مطالعۀ حاضر هدف ما بررسی کردن تأثیر اپی گالو کاتچین گالات بر نتایج آسیب مغزی پس از ضربه بود. مواد و روش ها: در یک آزمایش ب...
AIMS To explore the inhibitory effects of epigallocatechin gallate (EGCG) on the proliferation of colorectal cancer cells and on the gene expression of Notch signaling. METHODS The colorectal cancer cells and orthotopic colorectal cancer transplant model were treated with EGCG, and MTT assay was used to test the inhibitory role of EGCG in the proliferation of colorectal cancer cells. RESULT...
Purpose: Recent studies revealed the neuroprotective effects of green tea antioxidant on experimental cerebral ischemia, but these effects on spinal cord injury (SCI) has not yet been studied.Materials and Methods: Rats were randomly divided into three groups of 18 rats each as follows: sham group (laminectomy), control group (SCI) and experimental group (EGCG). Spinal cord samples were taken 2...
The aim of the study was to examine the effect of topical vehicles on the in vivo human stratum corneum penetration of the antioxidant and skin photoprotective agent (-)-epigallocatechin-3-gallate (EGCG). Model oil-in-water (o/w) emulsion and gel formulations containing 1 % (m/m) EGCG were prepared and subjected to photodegradation studies in order to select excipients that minimize the light i...
در پژوهش حاضر، قدرت آنتی¬اکسیدانی اسید گالیک و استر متیله آن، متیل گالات، و آلفا- توکوفرول به عنوان آنتی-اکسیدان شاهد (غلظت 200 پی¬پی¬ام) در تری¬آسیل¬گلیسرولهای روغن ماهی کیلکا و امولسیون روغن در آب آن مورد مطالعه قرار گرفت. سپس پایداری اکسایشی روغنها در چهار سطح غلظتی (200، 400، 800 و 1600 پی¬پی¬ام) در سه دمای 35، 45 و 55 درجه سانتیگراد از طریق آزمون پراکسید پایش گردید. همچنین قدرت مهارکنندگی ...
(-)-Epigallocatechin-3-gallate (EGCG), a major green tea polyphenol, has been shown to inhibit the proliferation of a variety of tumor cells. Epidemiological studies have shown that drinking green tea can reduce the incidence of nasopharyngeal carcinoma (NPC), yet the underlying mechanism is not well understood. In this study, the inhibitory effect of EGCG was tested on a set of Epstein Barr vi...
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