Chronically institutionalized geriatric (n = 174; average length of hospitalization = 35.1 years) and nongeriatric (n = 59; average length of hospitalization = 17.3 years) schizophrenia patients were classified with regard to their enduring negative symptoms (ENS) over a year. All patients completed neuropsychological tests that have been previously found to be implicated in geriatric schizophr...

The enteric nervous system (ENS) derives from migratory neural crest cells that colonize the developing gut tube, giving rise to an integrated network of neurons and glial cells, which together regulate important aspects of gut function, including coordinating the smooth muscle contractions of the gut wall. The absence of enteric neurons in portions of the gut (aganglionosis) is the defining fe...

The zebrafish enteric nervous system (ENS), like those of all other vertebrate species, is principally derived from the vagal neural crest. The developmental controls that govern the specification and patterning of the ENS are not well understood. To identify genes required for the formation of the vertebrate ENS, we preformed a genetic screen in zebrafish. We isolated the lessen (lsn) mutation...

OBJECTIVES Emergency nurses (ENs) typically place peripheral intravenous (IV) lines, but if repeated attempts fail, emergency physicians have to obtain peripheral or central access. The authors describe the patient population for which ultrasound (US)-guided peripheral IVs are used and evaluate the success rates for such lines by ENs. METHODS This was a prospective observational study of ENs ...

BACKGROUND & AIMS In the intestines, Toll-like receptor 2 (TLR2) mediates immune responses to pathogens and regulates epithelial barrier function; polymorphisms in TLR2 have been associated with inflammatory bowel disease phenotype. We assessed the effects of TLR2 signaling on the enteric nervous system (ENS) in mice. METHODS TLR2 distribution and function in the ileal neuromuscular layer of ...

The enteric nervous system (ENS) is a complex network of neurons and glia within the gut wall which originate from neural crest cells. Self-renewing, multipotential ENS progenitors have been isolated from the gut of foetal as well as adult rodents, however, the identity of the ENS progenitor and the regulation of its neurogenic potential invivo, are currently unknown. Sox10 is an HMG-containing...

We report two cases of epidermal nevus syndrome (ENS) involving the spine. MR imaging of the spine demonstrated intraspinal lipomas in both cases. Abnormal, enhancing, enlarged cervical and lumbosacral nerve roots were present in one patient. Spinal imaging for patients with ENS may help in the diagnosis of subtle intracranial manifestations, as it did in both of our cases. ENS has features sim...

Soutenue à Cachan le 30 Novembre 2012 devant le jury composé de : Francisco Chinesta École Centrale de Nantes Président Mohamed Ichchou École Centrale de Lyon Rapporteur Sergio De Rosa Professeur, Università di Napoli “Federico II” Rapporteur Robin S. Langley Professeur, University of Cambridge Examinateur Bernard Troclet Professeur, ENS de Cachan, EADS-Astrium Examinateur Pierre Ladevèze Profe...

The gastrointestinal tract harbors its own intrinsic nervous system, the enteric system (ENS). Nutrients, such as glucose, fatty acids, or amino indirectly modulate physiology of ENS. Moreover, recent studies have shown that gut microbiota is a key regulator ENS and development. Although most development occurs in utero, is, an environment devoid microbiota, maternal could influence offspring’s...