Treatment of [Mn(dpop)(H2O)2]Cl2 (dpop = 2,13-dimethyl-3,6,9,12,18-pentaazabicyclo-[12.3.1]octadeca-1(18),2,12,14,16-pentaene) with K4[Mo(CN)7]·2H2O under varied synthetic conditions afforded four different compounds: {[Mn(dpop)]4[(dpop)Mn(H2O)]2[Mo(III)(CN)7]3·27H2O}n (1), {[(dpop)Mn(H2O)][Mo(III)(CN)7][Mn(dpop)]3[Mo(IV)(CN)8]·29H2O}n (2), {[(dpop)Mn(H2O)]2[Mo(IV)(CN)8]2[Mn(dpop)]4[Mo(III)(CN)...

Calcineurin (Cn)-Aalpha-deficient mice develop abnormalities of postnatal kidney development, similar to that of cyclooxygenase (COX)-2-deficient mice. The present study was undertaken to examine expression and regulation of Cn isoforms in the developing kidney during the postnatal period and further characterize the relationship between Cn and COX-2. The protein expressions of all three Cn iso...

PURPOSE Cranial nerve (CN) palsy is the main symptom in patients with locally advanced nasopharyngeal carcinoma (NPC). This study aimed to evaluate the therapeutic outcome of NPC with CN palsy and to analyze the prognostic factors. PATIENTS AND METHODS A total of 104 NPC patients with CN palsy curatively treated by conventional (n=44) or conformal (n=60) radiotherapy (RT) were enrolled. Upper...

Cerebellar output is necessary for the ideal implementation of many nervous system functions, particularly motor coordination. A key step toward understanding the generation of this output is characterizing the factors that shape the activity of the cerebellar nuclei (CN). There are four major sources of synaptic input that modulate CN activity; collaterals of climbing and mossy fibers are two,...

The paper elaborates methodological basis of collaborative networks (CN) complex adaptation. We consider challenges and underlying principles of the CN complex adaptation. Subsequently, the DIMA-methodology of the integrated CN modeling is considered. The paper ends with the presentation of the fivelevel CN complex adaptation concept and summarizing DIMA-methodology application in the CN comple...

Chrysanthemum plants are one of the most economically important in South Korea. Both virus and viroid can cause diseases economic damage to plants. In this study, we investigated detection seven viruses two viroids 350 chrysanthemum cultivated Yesan-gun, Chungcheongnam-do. Two viruses, B (CVB) tomato aspermy (TAV), viroids, chlorotic mottle (CChMVd) stunt (CSVd), were detected study. The six sa...

BACKGROUND In transplant patients, current cyclosporine (CsA) dose monitoring with classic pharmacokinetics has demonstrated limitations. Evaluation of the activity of calcineurin (CN), the serine-threonine phosphatase enzyme target of CsA, has been proposed as a reliable way to optimize CsA dosing. METHODS CN activity was measured in whole blood in an attempt to overcome the high variability...