DAVID FULTON,1 ANDREAS PAPAPETROPOULOS,1 XIAOPING ZHANG,2 JOHN D. CATRAVAS,3 THOMAS H. HINTZE,2 AND WILLIAM C. SESSA1 1Department of Pharmacology, Boyer Center for Molecular Medicine, Yale University School of Medicine, New Haven, Connecticut 06536-0812; 2Department of Physiology, New York Medical College, Valhalla, New York 10595; and 3Vascular Biology Center and Department of Pharmacology and...

Supinski, G., D. Nethery, T. M. Nosek, L. A. Callahan, D. Stofan, and A. DiMarco. Endotoxin administration alters the force vs. pCa relationship of skeletal muscle fibers. Am J Physiol Regulatory Integrative Comp Physiol 278: R891–R896, 2000.—Recent work indicates that endotoxemia elicits severe reductions in skeletal muscle force-generating capacity. The subcellular alterations responsible for...

Randich, Alan, William J. Tyler, James E. Cox, Stephen T. Meller, Gary R. Kelm, and Satinder S. Bharaj. Responses of celiac and cervical vagal afferents to infusions of lipids in the jejunum or ileum of the rat. Am. J. Physiol. Regulatory Integrative Comp. Physiol. 278: R34–R43, 2000.— Multiunit celiac and single-unit cervical recordings of vagal afferents were performed before and during infus...

HERSHEL RAFF,1,2 ERIC D. BRUDER,1 BARBARA M. JANKOWSKI,1 AND THEODORE L. GOODFRIEND3 1Endocrine Research Laboratory, St. Luke’s Medical Center, Milwaukee 53215; 2Department of Medicine, Medical College of Wisconsin, Milwaukee 53226; and 3Wm. S. Middleton Memorial Veterans Hospital and the Departments of Medicine and Pharmacology, University of Wisconsin School of Medicine, Madison, Wisconsin 53705

Gstraunthaler, Gerhard, Thomas Holcomb, Elisabeth Feifel, Wenlin Liu, Nikolaus Spitaler, and Norman P. Curthoys. Differential expression and acid-base regulation of glutaminase mRNAs in gluconeogenic LLC-PK1FBPase1 cells. Am. J. Physiol. Renal Physiol. 278: F227– F237, 2000.—LLC-PK1-FBPase cells, which are a gluconeogenic substrain of porcine renal LLC-PK1 cells, exhibit enhanced oxidative meta...

Harada, Shuitsu, and Yasuo Kasahara. Inhibitory effect of gurmarin on palatal taste responses to amino acids in the rat. Am J Physiol Regulatory Integrative Comp Physiol 278: R1513–R1517, 2000.—Gurmarin (10 μg/ml), a protein extracted from Gymnema sylvestre, depressed significantly (40–50%) the phasic taste responses to sugars (sucrose, fructose, lactose, and maltose) and saccharin sodium recor...

Tolbert, Evelyn M., Joseph Weisstuch, Helen D. Feiner, and Lance D. Dworkin. Onset of glomerular hypertension with aging precedes injury in the spontaneously hypertensive rat. Am J Physiol Renal Physiol 278: F839– F846, 2000.—The changes in renal hemodynamics that develop with aging in spontaneously hypertensive rats (SHR) were examined. Micropuncture studies revealed that glomerular capillary ...

Vink, Hans, and Brian R. Duling. Capillary endothelial surface layer selectively reduces plasma solute distribution volume. Am. J. Physiol. Heart Circ. Physiol. 278: H285– H289, 2000.—We previously reported that a 0.4to 0.5-μmthick endothelial surface layer confines Dextran 70 (70 kDa) to the central core of hamster cremaster muscle capillaries. In the present study we used a variety of plasma ...

Ishine, Takaaki, Isabelle Bouchelet, Edith Hamel, and Tony J. F. Lee. Serotonin 5-HT7 receptors mediate relaxation of porcine pial veins. Am. J. Physiol. Heart Circ. Physiol. 278: H907–H912, 2000.—Isolated porcine pial veins in the presence of active muscle tone have been shown to exhibit rhythmic contractions (RC) that are inhibited by serotonin (5-HT) in a concentration-dependent manner. The ...

Naghashpour, M., and G. Dahl. Sensitivity of myometrium to CGRP varies during mouse estrous cycle and in response to progesterone. Am. J. Physiol. Cell Physiol. 278: C561–C569, 2000.—Calcitonin gene-related peptide (CGRP) inhibits contractions of the myometrium. Isometric force measurements on myometrial strips were carried out to monitor the inhibitory capacity of CGRP in the myometrium during...