In the condensation of the 4and 5-nitro-substituted 2-acetyl-1,3-indandione with heteroaryl aldehydes in the presence of alkaline or acidic catalysts, the corresponding cinnamoyl derivatives are obtained that possess anticoagulant activity, compared with that of 2-acetyl-1,3-indandione. It has been proven that some of the sodium salts of the cinnamoyl-indandione possess anticoagulant activity. ...

Recent studies in mammals have documented the neural expression and mobility of retrotransposons and have suggested that neural genomes are diverse mosaics. We found that transposition occurs among memory-relevant neurons in the Drosophila brain. Cell type-specific gene expression profiling revealed that transposon expression is more abundant in mushroom body (MB) αβ neurons than in neighboring...

The lysosomal storage disorder mucolipidosis III αβ is caused by mutations in the αβ subunits of UDP-GlcNAc:lysosomal enzyme N-acetylglucosamine-1-phosphotransferase (phosphotransferase). This Golgi-localized enzyme mediates the first step in the synthesis of the mannose 6-phosphate recognition marker on lysosomal acid hydrolases, and loss of function results in impaired lysosomal targeting of ...

Dedicated to Louis Nirenberg with admiration and friendship In this talk I describe some recent joint work with Louis. Please see [8] for details. Let D be a bounded domain in R n. For positive constants 0 < λ ≤ Λ < ∞, let A(λ, Λ) denote the class of measurable coefficients {A αβ ij (x)}, 1 ≤ α, β ≤ n, 1 ≤ i, j ≤ N, which satisfy |A αβ ij (x)| ≤ Λ ∀ α, β, i, j, and x ∈ D, (1) and D

The Multi-model search framework generalizes minimax to allow exploitation of recursive opponent models. In this work we consider adding pruning to the multi-model search. We prove a sufficient condition that enables pruning and describe two pruning algorithms, αβ∗ and αβ∗ 1p. We prove correctness and optimality of the algorithms and provide an experimental study of their pruning power. We show...

copper (ii) phthalocyanine and 2, 9, 16, 23 tetrakis nitro copper (ii) phthalocyanine has been synthesized respectively from phthalonitrile and 4-nitro phthalonitrile under solvent-free condition using two different catalysts over nanodimensional zeolites. 4-nitro phthalonitrile synthesized from phthaimide in three steps. the newly prepared compounds have been characterized by ir, uv-vis,1h nm...

This paper introduces the idea of pre-searching a position—searching it before αβ determines that it needs to be searched. Consider the case where an iteration of αβ search comes across a position p that needs to be searched to depth d1, and the transposition table reveals that p will likely need to be searched later in that iteration to depth d2 greater than d1. Pre-searching involves speculat...

In our research, new bis-α, β-unsaturated carbonyl compounds (Z2-Z4) were prepared via Claisen- Schmidt reaction, by the condensation of 2,6-dimethyl-3,5-diacetyl-1,4-dihydropyridine (Z1) with different appropriate benzaldehyde, like (benzaldehyde, m-nitro benzaldehyde and o-chloro benzaldehyde) using 10% aqueous sodium hydroxide as a base. A simple efficient method has been applied for synthes...

A plethora of enhancements are available to be used together with the αβ search algorithm. There are so many, that their selection and implementation is a non-trivial task, even for the expert. Every domain has its specifics which affect the search tree Even seemingly minute changes to an evaluation function can have an impact on the characteristics of a search tree. In turn, different tree cha...