Alireza Sarkaki
Department of Physiology, School of Medicine, Ahvaz Jundishapur University of medical Sciences, Ahavaz, Iran
[ 1 ] - Gallic acid and exercise training improve motor function, nerve conduction velocity but not pain sense reflex after experimental sciatic nerve crush in male rats
Objective: The aim of present study was to evaluate the effects of oral administration of gallic acid (GA) for 21 days alone and in combination with exercise on nerve conduction velocity and sensory and motor functions in rats with sciatic nerve crush. Materials and Methods: Seventy adult male Wistar rats (250-300 g) were divided randomly into 7 groups with 10 in each: 1) Control (Cont), 2) Cru...
[ 2 ] - Pomegranate seed hydroalcoholic extract improves memory deficits in ovariectomized rats with permanent cerebral hypoperfusion /ischemia
Objective: Estrogen deficit following menopause results in cognitive behaviors impairment. Severity of these impairments in menopause women suffer with cerebral hypo perfusion/ischemia (HI) cause the brain damage and neuronal death. This study aimed to evaluate the effects of pomegranate seed extract (PGSE) on avoidance memories after permanent bilateral common carotid arteries occlusion (2CCAO...
[ 3 ] - Antidiabetic effect of honey feeding in noise induced hyperglycemic rat: involvement of oxidative stress
Objective(s):In this study the effect of oral administration of honey on serum glucose, lipids, stress oxidative markers, and morphology of langerhans islets in noise induced hyperglycemic rats was investigated. Materials and Methods: Male Wistar rats were divided into control, hyperglycemic, honey treated control, and honey treated hyperglycemic groups. For induction of hyperglycemia, noise s...
[ 4 ] - Ellagic acid improves hyperalgesia and cognitive deficiency in 6-hydroxidopamine induced rat model of Parkinson’s disease
Objective(s):Parkinson's disease (PD) is known for motor impairments. But often, there are non-motor symptoms such as cognitive deficiency and pain misperception, owing to possible role of nigrostriatal pathway. Antioxidants have protective effect on free radical-induced neuronal damage in PD. To further address, we examined the effects of ellagic acid (EA) in a rat model of PD induced by 6-hyd...
[ 5 ] - Ellagic Acid Protects the Brain Against 6-Hydroxydopamine Induced Neuroinflammation in a Rat Model of Parkinson’s Disease
Introduction: Neuroinflammation may play as an important risk factor in progressive degeneration of dopaminergic cells. Antioxidants have protective effects against free radicalsinduced neural damage in Parkinson’s disease (PD). In the present study, we examined the effects of ellagic acid (EA) on locomotion and neuroinflammatory biomarkers in a rat model of PD induced by 6-hydroxidopamin...
[ 6 ] - Effect of Ovariectomy on Reference Memory Version of Morris Water Maze in Young Adult Rats
Background: The effect of ovariectomy and accompanying sudden loss of circulating gonad hormones on spatial learning performance in the young adult rats was examined. We hypothesized that spatial learning and memory in a considerable number of women who undergo a surgical menopause and estrogen deprivation before their natural menopause be impaired. Methods: In this study, we used 26 Wistar ra...
[ 7 ] - اثر اسید گالیک بر حافظه اجتنابی غیر فعال در موش های صحرایی ماده بالغ تحت شرایط ایسکمی کامل مغزی
اهداف: ایسکمی مغزی حالتی است که به تمام یا بخش‌هایی از مغز، خون و در نتیجه اکسیژن کافی نمی‌رسد. با توجه به عوارض ناتوان‌کننده ایسکمی مغزی، این پژوهش با هدف بررسی اثر اسیدگالیک بر میزان حافظه اجتنابی غیرفعال در موش‌های صحرایی ماده بالغ، تحت شرایط ایسکمی دوطرفه مغز، انجام شد. روش‌ها: 84 سر موش صحرایی به‌طور تصادفی به 6 گروه 14تایی کنترل (C؛ بدون هرگونه دستکاری شریان کاروتید و تیمار)، کنترل اسیدگ...
نویسندگان همکار