Mohammad Kamalinejad
Department of Pharmacognosy, School of Pharmacy, Shaheed Beheshti University of Medical Sciences, Tehran, Iran
[ 1 ] - A review on botanicals with wound healing activity for pemphigus vulgaris: perspective of traditional Persian medicine and conventional medicine
Objective: As a rare autoimmune disease, pemphigus vulgaris has a poor prognosis especially in lack of proper medical support. This blistering disease involves both the skin and mucus membranes. The challenge is improving the healing process of skin lesions of which, superimposed infections are among the main causes of the disease mortality. Accordingly, we aimed to assess the treatment options...
[ 2 ] - Cassia fistula: A remedy from Traditional Persian Medicine for treatment of cutaneous lesions of pemphigus vulgaris
Objective: Pemphigus is a rare autoimmune disease that may be fatal without proper medical intervention. It is a blistering disease that involves both the skin and mucus membranes, in which the most important causes of death comprise superimposed opportunistic infections and complications of long-term high-dose corticosteroid therapy or prolonged consumption of immune suppressant drugs. Skin le...
[ 3 ] - Functional dyspepsia: A new approach from traditional Persian medicine
Objective: One of the most common global disorders is related to gastrointestinal system. Functional dyspepsia (FD) defined as upper abdominal pain and discomfort in the absence of organic ailments is a prevalent disease without any confirmed medication. The purpose of this study was to find gastric disorders which might be coincidental to FD based on traditional Persian medicine (TPM). Materia...
[ 4 ] - Omega-3 and omega-6 content of medicinal foods for depressed patients: implications from the Iranian Traditional Medicine
Objectives: Considering the increasing prevalence of depression in modern societies and the positive effects of omega-3 polyunsaturated fatty acids on depression, this study aims to investigate the omega-3 and omega-6 content of various foodstuffs, prescribed or prohibited by Iranian Traditional Medicine (ITM). Materials and Methods: Firstly, reliable sources of Iranian Traditional Medicine wer...
[ 5 ] - Effect of Melissa officinalis (lemon balm) on sexual dysfunction in women: A double- blind, randomized, placebo-controlled study
Hypoactive sexual desire disorder (HSDD) is the most prevalent female sexual dysfunction (FSD) and its bio-psychosocial multifactorial etiology justifies its multifaceted treatment. In Iranian Traditional Medicine (ITM), the weakness of the main organs (heart, brain and liver) is one of the important causes of lack of sexual desire; hence, their strengthening is a priority during treatment. Mel...
[ 6 ] - Anxiolytic-Like and Sedative Effects of Alcea Aucheri (Boiss.) Alef. Flower Extract in the Laboratory Rat
The present study was conducted to investigate the possible anxiolytic and sedative ofan acute administration and 4-day repeated dosing of an aqueous extract of flowers of Alceaaucheri (Boiss.) Alef. (EFA) in rats subjected to the elevated plus-maze (EPM), open-field, andhorizontal wire tests. All drugs were administered intraperitoneally. Phytochemical screeningconfirmed the presence of phenol...
[ 7 ] - Does regular use of a complementary medicine of Olea Europe and Ficus carica have adverse effects on lipid profile and fasting blood glucose of Rheumatoid Arthritis (RA) patients under treatment with DMARD regimens containing methotrexate?
Rheumatoid arthritis (RA) patients are vulnerable to cardiovascular morbidity and mortality in which atherosclerosis plays a major role. In this study, the lipid profile and fasting blood sugar (FBS) of RA patients receiving a complementary medicine of olive and fig, as add-on therapy for routine disease-modifying antirheumatic drugs (DMARDs) regimen containing low dose methotrexate (MTX), were...
[ 8 ] - Hypolipidemic, hepatoprotective and renoprotective effects of Cydonia oblonga Mill. Fruit in streptozotocin-induced diabetic rats
Diabetes mellitus is associated with complications in several different systems of the body, and the incidence of diabetes is rapidly increasing worldwide. The objective of the present study was to evaluate the effect of aqueous extract of Cydonia oblonga Mill. Fruit on lipid profile and some biochemical parameters in streptozotocin-induced diabetic rats. The extract showed anti hyper lipidemic...
[ 9 ] - Total Phenolic Content and Antibacterial Activity of Five Plants of Labiatae against Four Foodborne and Some Other Bacteria
The aim of this study was to evaluate the antibacterial effects of Thymus vulgaris, Thymus caramanicus, Zataria multiflora, Ziziphora clinopodioides and Ziziphora tenuior against four foodborne and four other bacteria including Staphylococcus aureus, Shigella dysenteriae, Salmonella typhimurium, Escherichia coli, Staphylococcus epidermidis, Bacillus subtilis, MRSA and Pseudomona aeruginosa and ...
[ 10 ] - Effect of Adiantum Capillus veneris Linn on an Animal Model of Testosterone-Induced Hair Loss
Androgenetic alopecia is the most common form of hair loss in men. The present study was designed to evaluate the hair growth-promoting activity of a preparation of the Adiantum capillus veneris Linn. (A. capillus veneris Linn.) on albino mice using a testosterone-induced alopecia model. Five groups of albino mice were studied: (A) Testosterone solution only (n=6); (B) Testosterone + Finasteri...
[ 11 ] - Evaluation of Anti-Inflammatory and Anti-Nociceptive Effects of Defatted Fruit Extract of Olea europaea
Fruits of Olea europaea L. have been used for centuries in folk medicine to treat many inflammatory diseases. In order to evaluate the anti-nociceptive activities of the methanolic and aqueous extracts of defatted fruits of O. europaea, formalin test was used and for evaluation of anti-inflammatory effects of the extract, the volume of paw edema was measured. The results revealed that both extr...
[ 12 ] - Effect of Melissa officinalis (lemon balm) on sexual dysfunction in women: A double- blind, randomized, placebo-controlled study
Hypoactive sexual desire disorder (HSDD) is the most prevalent female sexual dysfunction (FSD) and its bio-psychosocial multifactorial etiology justifies its multifaceted treatment. In Iranian Traditional Medicine (ITM), the weakness of the main organs (heart, brain and liver) is one of the important causes of lack of sexual desire; hence, their strengthening is a priority during treatment. Mel...
[ 13 ] - Anxiolytic-Like and Sedative Effects of Alcea Aucheri (Boiss.) Alef. Flower Extract in the Laboratory Rat
The present study was conducted to investigate the possible anxiolytic and sedative ofan acute administration and 4-day repeated dosing of an aqueous extract of flowers of Alceaaucheri (Boiss.) Alef. (EFA) in rats subjected to the elevated plus-maze (EPM), open-field, andhorizontal wire tests. All drugs were administered intraperitoneally. Phytochemical screeningconfirmed the presence of phenol...
[ 14 ] - Does regular use of a complementary medicine of Olea Europe and Ficus carica have adverse effects on lipid profile and fasting blood glucose of Rheumatoid Arthritis (RA) patients under treatment with DMARD regimens containing methotrexate?
Rheumatoid arthritis (RA) patients are vulnerable to cardiovascular morbidity and mortality in which atherosclerosis plays a major role. In this study, the lipid profile and fasting blood sugar (FBS) of RA patients receiving a complementary medicine of olive and fig, as add-on therapy for routine disease-modifying antirheumatic drugs (DMARDs) regimen containing low dose methotrexate (MTX), were...
[ 15 ] - Hypolipidemic, hepatoprotective and renoprotective effects of Cydonia oblonga Mill. Fruit in streptozotocin-induced diabetic rats
Diabetes mellitus is associated with complications in several different systems of the body, and the incidence of diabetes is rapidly increasing worldwide. The objective of the present study was to evaluate the effect of aqueous extract of Cydonia oblonga Mill. Fruit on lipid profile and some biochemical parameters in streptozotocin-induced diabetic rats. The extract showed anti hyper lipidemic...
[ 16 ] - Total Phenolic Content and Antibacterial Activity of Five Plants of Labiatae against Four Foodborne and Some Other Bacteria
The aim of this study was to evaluate the antibacterial effects of Thymus vulgaris, Thymus caramanicus, Zataria multiflora, Ziziphora clinopodioides and Ziziphora tenuior against four foodborne and four other bacteria including Staphylococcus aureus, Shigella dysenteriae, Salmonella typhimurium, Escherichia coli, Staphylococcus epidermidis, Bacillus subtilis, MRSA and Pseudomona aeruginosa and ...
[ 17 ] - Effect of Adiantum Capillus veneris Linn on an Animal Model of Testosterone-Induced Hair Loss
Androgenetic alopecia is the most common form of hair loss in men. The present study was designed to evaluate the hair growth-promoting activity of a preparation of the Adiantum capillus veneris Linn. (A. capillus veneris Linn.) on albino mice using a testosterone-induced alopecia model. Five groups of albino mice were studied: (A) Testosterone solution only (n=6); (B) Testosterone + Finasteri...
[ 18 ] - Evaluation of Anti-Inflammatory and Anti-Nociceptive Effects of Defatted Fruit Extract of Olea europaea
Fruits of Olea europaea L. have been used for centuries in folk medicine to treat many inflammatory diseases. In order to evaluate the anti-nociceptive activities of the methanolic and aqueous extracts of defatted fruits of O. europaea, formalin test was used and for evaluation of anti-inflammatory effects of the extract, the volume of paw edema was measured. The results revealed that both extr...
[ 19 ] - مروری بر گیاه سداب graveolens L. Ruta، کاربرد آن در طب سنتی و یافتههای تحقیقات نوین
بر طبق مدارک موجود، گیاه سداب از کهنترین گیاهان مورد استفاده در طب سنتی ایران و ملل مختلف بوده و برای درمان بسیاری از بیماریها کاربرد داشته است. در حال حاضر نیز به علت اثرات جالب و گاه منحصر به فرد آن هنوز در میان اقوام مختلف جهان به مصرف می رسد. تاکنون برخی از کارآییهای این گیاه به عنوان ضدالتهاب، ضدسرطان، ضدآریتمی و فشارخون، ضدمیکروب، قارچ و انگل، کاهنده برخی از فعالیتهای سیستم عصبی و ضد...
[ 20 ] - Effect of administration of Teucrium polium on blood glucose and lipid levels in
Introduction: Recently, the search for appropriate hypoglycemic agents has been focused on plants. Teucrium polium is traditionally used in Iran to manage, control and treat diabetes. We designed this study to elucidate the effect of the administration of oral doses of aqueous and ethanol extract from Teucrium polium on plasma glucose, lipid profiles and liver enzymes in diabetic and non dia...
[ 21 ] - The Effect of Elaeagnus angustifolia L. Cream on Radiation-Induced Skin Reactions in Women with Breast Cancer; A Preliminary Clinical Trial
Radiotherapy, a highly effective way to destroy breast cancer, causes skin adverse effects. A considerable amount of studies have been conducted to find a way to alleviate or relieve dermal adverse effects of radiation. The aim of this study was to observe the clinical effect of Elaeagnus angustifolia L. cream to treat radiotherapy-induced skin destruction in breast cancer patients. thirt...
[ 22 ] - The Role of Olea Europaea L. Fruit on A2780, A172 and HFFF2 Proliferation
Olea europaea L. commonly known as olive has been traditionally used for the prevention and treatment of many diseases since ancient times. Olive has been reported to possess a broad spectrum of pharmacological properties. In the present study we investigated the activity of aqueous extract of Olea europaea L. fruit at various concentrations on A2780, A172 and HFFF2 cell lines proliferation by ...
[ 23 ] - The effects of hawthorn (Crataegus monogyna) syrup on gastroesophageal reflux symptoms
Background and objectives: Gastroesophageal reflux is a common chronic disease that impairs individuals’ quality of life, wherein patients should receive prolonged, and sometimes lifelong, treatment with chemical drugs, that in addition to high costs they can lead to side effects in the long term .Hawthorn fruit is one of the drugs used in traditional medicine to relieve reflux symptoms and to ...
[ 24 ] - Phoenix dactylifera L. Fruit Induces Cell Proliferation of A2780, A172 and HFFF2 Cell Lines
Dates fruit has been used as staple food in the Middle East for thousands of years and various types of dates are found worldwide. Dates and their constituents show various roles in diseases prevention and treatment through anti-oxidant, anti-inflammatory, anti-bacterial activity. In the present study we investigated the activity of aqueous and n-hexane extracts of Phoenix dactylifera L. fruit ...
[ 25 ] - Topical application of Cassia fistula L. fruit gel in management of cutaneous lesions of pemphigus vulgaris: A double-blind, placebo-controlled clinical trial
Objective: Cassia fistula L. fruit extract has been traditionally used in the treatment of pemphigus vulgaris (PV) lesions in Iran. The aim of this study was to determine the efficacy of C. fistula fruit gel on healing time of PV lesions in a clinical setting.Materials and Methods: This was a randomized, double-blind placebo-controlled clinical trial that was performed in dermatology ward at Sa...
[ 26 ] - Effects of Boswellia serrata resin extract on motor dysfunction and brain oxidative stress in an experimental model of Parkinson’s disease
Objective:Boswellia serrata oleo-gum resin (frankincense) exerted antioxidant and anti-inflammatory effects against several diseases, such as; asthma, rheumatoi...
[ 27 ] - Comparative Study of the Effects of Chamomile (Matricaria Chamomilla L.) and Cabergoline on Idiopathic Hyperprolactinemia: A Pilot Randomized Controlled Trial
Chamomile is a fascinating plant quoted in several traditional medicine texts, which hasbroad-spectrum pharmacological activity and medicinal uses. The aim of this study was toassess the efficacy of chamomile syrup in reducing serum prolactin in women with idiopathichyperprolactinemia. The study was a randomized, controlled clinical trial that was cond...
[ 28 ] - Comparative Study of the Effects of Chamomile (Matricaria Chamomilla L.) and Cabergoline on Idiopathic Hyperprolactinemia: A Pilot Randomized Controlled Trial
Chamomile is a fascinating plant quoted in several traditional medicine texts, which hasbroad-spectrum pharmacological activity and medicinal uses. The aim of this study was toassess the efficacy of chamomile syrup in reducing serum prolactin in women with idiopathichyperprolactinemia. The study was a randomized, controlled clinical trial that was cond...
[ 29 ] - Comparison of Radiation-Induced Mucositis With Multiple Oral Ulcers Based on Iranian Traditional Medicine: A Review Study
Objective Radiation-Induced Mucositis (RIM) is more common in patients with head and neck cancers. Common medications have not been fully successful in preventing and treating RIM. We can use the potential of Iranian medicine for prevention and oral/topical treatment of these lesions. Methods In this review study, the keywords of “Mucositis”, “Head and Neck Radiotherapy”, “Aphthous”, and “Mou...
[ 30 ] - Review of skin cancers terminology, etiology and treatment from ancient Persian medicine view point
Background: Skin cancers are the most prevalent type among the white with an increasing trend of incidence around the world and Iran. Scientific developments in diagnosing these cancers and using screening methods and utilizing treatment methods have contributed to the relative control of the cancer. Hence, it is necessary to consider other suggested approaches of complementary and traditional ...
[ 31 ] - Anticonvulsant Effect of Alcea aucheri on Pentylenetetrazole and Maximal Electroshock Seizures in Mice
Introduction: This study was designed to investigate the possible anticonvulsant effect of acute administration of an aqueous extract of flowers of Alcea aucheri (EFA) in a seizure model. Methods: Seizures were induced in male adult Swiss mice by administration of pentylenetetrazol (PTZ) or Maximal Electroshock (MES). Mice were randomly subjected to receive saline, EFA (8.75-175 mg.kg-1), or d...
[ 32 ] - A search for protective activity of aqueous extract of Punica granatum var. pleniflora against CCl4-induced hepatotoxicity in rats
Background: Punica granatum var. pleniflora (Golnar in Persian) is a subspecies of pomegranate that only has the blooms with no fruit generation. The plant has been used for the treatment of liver diseases in Iranian folk medicine. Objective: In the present study, the hepatoprotective effects of aqueous extract of Punica granatum var. pleniflora (APG) were evaluated in carbon tetrachloride (CCl...
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