Mahnoosh Fatemi

[ 1 ] - The effect of Ficus carica latex on 7, 12-dimethylbenz (a) anthracene-induced breast cancer in rats

Objective: In traditional medicine, Ficus carica (also known as fig) latex is recognized as a remedy with various therapeutic effects. Recently, in vitro studies have reported the anticancer effect of this latex on cancer cell lines. This study evaluated the effect of this latex on breast cancer growth, hematological parameters, and histopathology in rats. Materials and Methods: Twenty-four fem...

[ 2 ] - Effects of silver nanoparticle on the developing liver of rat pups after maternal exposure

Abstract The extensive application of silver nanoparticles (AgNPs) has been increased due to their antimicrobial properties, however numerous concerns has been arisen about their toxicity potential. Since nanoparticles can cross through the placenta and accumulate in the embryonic organs especially liver, in this study, developmental hepatotoxicity of AgNPs was investigated. Pregnant rats were...

[ 3 ] - Effects of silver nanoparticle on the developing liver of rat pups after maternal exposure

Abstract The extensive application of silver nanoparticles (AgNPs) has been increased due to their antimicrobial properties, however numerous concerns has been arisen about their toxicity potential. Since nanoparticles can cross through the placenta and accumulate in the embryonic organs especially liver, in this study, developmental hepatotoxicity of AgNPs was investigated. Pregnant rats were...

[ 4 ] - Protective Effect of Lactobacillus fermentum on Lead-induced Hematological and Body Weight Alterations in Rats

Background: Lead is known to be a highly toxic heavy metal which has a wide range of effect on human health. It has been proven that probiotics are able to bind heavy metals and remove them from the environment. In this study, the effect of Lactobacillus fermentum (L. fermentum) and its cytoplasmic extract were investigated on the hematological and body weight parameters in lead exposed rats. ...

[ 5 ] - Study of Antioxidant Effects of Selenium-Enriched Saccharomyces Boulardii on Staphylococcus Aureus Infection

Background: The most important strategy of the immune system against pathogens is producing active oxygen intermediates with sidelong consequence of oxidative stress induction in body. Probiotics and selenium have recently been proven to be powerful antioxidants that help boost the immune system. Hence, the aim of this study was to investigate the antioxidant effects of Sac...

[ 6 ] - The Effect of Lactobacillus Fermentum against Lead-Induced Oxidative Damages in Rat Kidneys

Background: Kidneys are the most vulnerable organs with respect to oxidative stress caused by lead poisoning. In this study, renal biomarkers were investigated in rats, exposed to lead after treatment with or without Lactobacillus fermentum. Methods: Twenty-four rats were divided into four groups of five each as follows: a) control, b) lead-exposed, c) Lactobacillus fermentum–treated, and d)...