Mostafa Ghanei
Chemical Injuries Research Center, Baqiyatallah University of Medical Sciences, Tehran, Iran
[ 1 ] - Pulmonary Scintiscan Findings in Sulfur Mustard Injured Patients Suspected for Gastroesophageal Reflux; a Descriptive Cross-Sectional Study
Background:Gastroesophageal reflux disease (GERD) prevalence in patients with sulfur mustard (SM)-induced bronchiolitis obliterans (BO) is higher than exposed cases with mild lung injuries. In this study, we aimed to evaluate the prevalence of microaspirations using nuclear scintiscan among BO patients with SM exposure. Methods: This was a prospective cross-sectional study conducted on patient...
[ 2 ] - Spirometric Findings in TNT Factory Workers Compared with Unexposed Controls
Background: Trinitrotoluene (TNT) is one of the most well-known and oldest explosive agents. In the recent decade, bioenvironmental, biochemical, and biological effects of TNT exposure have been more in the spotlight. In this study, we aimed to evaluate spirometric parameters in workers of a TNT factory exposed to TNT and other related fumes and dusts compared with the unexposed controls. Metho...
[ 3 ] - Study on Effectiveness of Low Dose Theophylline as Add-on to Inhaled Corticosteroid for Patients with Sulfur Mustard Induced Bronchiolitis
Background: Theophylline may reverse steroid resistance and decrease inflammation in patients with chronic pulmonary disease and sulfur mustard (SM) induced bronchiolitis. This study was designed to assess the effects of low-dose theophylline on improvement of pulmonary function tests (PFTs) of SM exposed patients.Methods: In this comparative observational study, a group of SM-exposed victims d...
[ 4 ] - Promising role for Gc-MAF in cancer immunotherapy: from bench to bedside
Immunotherapy has been used for years in many types of cancer therapy. Recently, cancer immunotherapy has focused on mechanisms which can enhance the development of cell-mediated immunity. Anticancer medications are administered to inhibit immunosuppressive factors such as nagalase enzyme, which is produced by neoplastic cells and destroys macrophage activating factor (Gc-MAF). Anti-neoplastics...
[ 5 ] - بررسی اثر کلسیم سولفات در کنترل خونریزی کبدی در مدل حیوانی
Background: The control of parenchymal hemorrhage especially in liver parenchyma, despite surgical science progresses is still one of the challenges surgeons face saving the patients’ lives and there is a research challenge between the researchers in this field to introduce a more effective method. This study aimed to determine the hemostatic effect of calcium sulfate on controlling the bleedin...
[ 6 ] - The Role of Serum Level of Interleukin-6 in Severity of Pulmonary Complications of Sulfur Mustard Injuries
Diverse studies suggest that interleukin-6 (IL6), as a member of cytokines family, has a major role in inflammatory processes of airways and lungs. In this study, an attempt was made to determine the serum level of IL6 in sulfur mustard (SM) injured patients and its comparison with controls. The measured IL6 mean level in patients with chemical injuries (0.76±0.3 ng/ml) was significantly higher...
[ 7 ] - The Respiratory Toxicities of Mustard Gas
Sulfur mustard is one of the major potent chemical warfare agents. It was widely used against not only military personnel but also civilian people ofIranduring the last years (1984–1988) of the Iraq–Iran war. A number of studies were performed regarding the acute and long-term consequences of sulfur mustard on respiratory system. Currently, many aspects of leading respiratory disorder that was ...
[ 8 ] - Accuracy of Impulse Oscillometry in Airway Dysfunction
Background: The purpose of this study was to calculate and compare the specificity and sensitivity of impulse oscillometry (IOS) as a new technique in the detection of airways dysfunction by means of a simple pulmonary function test in chemical warfare injured cases suffering from respiratory diseases. Methods: The study was performed prospectively in 100 patients, who complained of dyspnea as ...
[ 9 ] - Clinical Review of Mustard Lung
More than 45,000 of 100,000 exposed patients are suffering from late effects of sulfur mustard (SM) after almost 20 years post-exposure. Respiratory complications of SM exacerbate over time and are the greatest cause of long-term disability in exposed patients. A triad of cough, expectoration and dyspnea has been found to be the main symptoms among patients. Even those who had not developed acu...
[ 10 ] - بررسی نگاشت نهادی نظام تنظیمگری زیستفناوری در ایران؛ مطالعه موردی: غذا و داروی مبتنی بر زیستفناوری
موضوعی که در سالهای اخیر در بحث تنظیمگری موردتوجه قرارگرفته است، تنظیمگری محصولات مبتنی بر فناوریهای نوظهور ازجمله زیستفناوری میباشد. ازاین‌رو هدف اصلی این پژوهش تحلیلنظام تنظیمگری زیستفناوری کشور در بخش غذا و دارو میباشد. بدین منظور در این پژوهش ابتدا نگاشت نهادی این حوزه ترسیم شده است. سپس از طریق مطالعه نظام تنظیمگری زیستفناوری در س...
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