Hossein Babaei
Drug Applied Research Center, Tabriz University of Medical Sciences, Tabriz, Iran & Department of Pathobiology, Faculty of Veterinary, University of Tehran, Tehran, Iran
[ 1 ] - Evaluation of Cytotoxic Effect and Antioxidant Activity of Grape Seed Extract, Crocin, and Phenytoin
Antioxidant compounds inhibit formation of free radicals, chelate catalytic metals, and scavenge free radicals in biological systems. In addition, antioxidants play a decisive role in prevention of numerous physiological dysfunctions, cancers, and metabolic disorders. This study sought to evaluate the antioxidant capacity and cytotoxic effect of grape seed extract (GSE), crocin (CRO), and pheny...
[ 2 ] - تاثیر مصرف مکمل عصاره‌ی هسته‌ی انگورVitis Vinifera) ) بر پروفایل لیپیدی در بیماران دیابتی نوع 2
مقدمه: ناهنجاری‌های لیپیدی یکی از اصلی‌ترین عوامل ایجاد کننده‌ی بیماری‌های قلبی ـ عروقی در بیماران دیابتی نوع 2 می‌باشد. پژوهش حاضر برای بررسی اثرات مکمل عصاره‌ی هسته‌ی انگور [grape seed extract (GSE)] بر پروفایل لیپیدی سرم در بیماران دیابتی نوع 2 طراحی گردید. مواد و روش‌ها: پژوهش حاضر به روش کارآزمایی بالینی سه سو کور انجام شد. 48 بیمار دیابتی به شکل تصادفی به دو گروه مکمل عصاره‌ی هسته‌ی انگور...
[ 3 ] - Protective Effects of Hydroalcoholic Extract of Nasturtium officinale on Rat Blood Cells Exposed to Arsenic
Background: Arsenic is one of the most toxic metalloids. Anemia and leukopenia are common results of poisoning with arsenic, which may happen due to a direct hemolytic or cytotoxic effect on blood cells. The aim of this study was to examine the effects of hydroalcoholic extract of Nasturtium officinale on blood cells and antioxidant enzymes in rats exposed to sodium (meta)arsenite. Methods: 32...
[ 4 ] - Impact of Consumption of Chicory Leaf Extract in Adjunct with Non-surgical Periodontal Therapy on Serum Antioxidant and Lipid Status in Patients with Periodontal Disease: Preliminary Study
Background and Objectives: Periodontal disease is a chronic disorder with a high prevalence. There are few studies about the role of diet in prevention and treatment of periodontal disease. The aim of this study was to evaluate the effect of consumption of Chicory leaf extract in adjunct with non-surgical periodontal therapies on serum antioxidant and lipid status. Materials and Methods: Thi...
[ 5 ] - Ultrastructural and Echocardiographic Assessment of Chronic Doxorubicin-Induced Cardiotoxicity in Rats
Doxorubicin (DOX) is one of the secondary metabolites of Streptomyces peucetius var. caesius. It is a common and effective chemotherapeutic agent used for the treatment of different diseases, including lymphoma, leukemia, breast cancer, and solid tumors. However, this medicine causes cardiotoxic side effects, which limit its clinical application. The present study examined the cardiomy...
[ 6 ] - The Effects of Grape Seed Extract Supplementation on Exercise-Induced Oxidative Stress in Young Untrained Males
Background and purpose: The aim of this study was to determine the effect of acute aerobic exercise and 14-days grape seed extract supplementation on total antioxidant capacity, lipid peroxidation, and muscle cell damage biomarkers in untrained males. Materials and Methods: In a randomized, double-blinded, and placebo-controlled study, twenty-two male students (age 19±1 years, weight 67.44±7 k...
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