Shahram Lotfi
Department of chemistry, Payame Noor University (PNU),19395-4697 Tehran, I.R. of Iran
[ 1 ] - Electrosynthesis of Clozapine Drug Derivative via an EC Electrochemical Mechanism
The fact that oxidation, as one of the main routes of phase I metabolism of drugs, follows by conjugation reactions, and also formation of nitrenium ion as one of the clozapine oxidation products, directed us to investigate the oxidation of clozapine (CLZ) in the presence of nucleophile. The oxidation of clozapine (CLZ) has been studied on a glassy carbon electrode in the absence and presence o...
نویسندگان همکار