محمود وکیلی
دانشیار گروه پزشکی اجتماعی، مرکز تحقیقات پایش سلامت، دانشکده پزشکی، دانشگاه علوم پزشکی شهید صدوقی یزد، یزد، ایران.
[ 1 ] - بررسی ارتباط بین پلی‌مورفیسم rs2488457 ژن PTPN22 و سقط مکرر
مقدمه: سقط مکرر به ختم بارداری بیش از دو بار اطلاق می‌شود. عوامل متعددی در ایجاد سقط مکرر دخیل هستند، وجود اختلال در عملکرد سیستم ایمنی منجر به دفع جنین می‌شود. آنزیم پروتئین تیروزین فسفاتاز بافت لنفاوی (Lyp) که توسط ژن PTPN22 کد می‌شود، نقش حیاتی در تنظیم و تعادل پاسخ‌های ایمنی دارد؛ به‌تازگی پلی‌مورفیسم rs2488457که در ناحیه پروموتر این ژن قراردارد کشف شده است، محتمل است این پلی‌مورفیسم با تغ...
[ 2 ] - بررسی میزان رعایت حقوق بیماران و ضرورت آن از دیدگاه بیماران بستری شده در بیمارستان شهید صدوقی یزد-1391
Introduction:Efficient health system needs active participation and good relationship between health care providers and health care recipient. The fundamental reason for the importance attached to patient’s rights and the corresponding increase in legislation is that respecting patient’s rights is an essential part of providing good health care. Existence of patient rights prism doesn't mean it...
[ 3 ] - بررسی مقاومت آنتی‌بیوتیکی و فراوانی ژن‌های اگزاسیلینازی blaOXA-23 و blaOXA-24 در جدایه‌های اسینتوباکتر بومانی از نمونه‌های تراشه بیماران بستری در بخش مراقبت‌های ویژه بیمارستان‌های شهر اصفهان
Introduction: Acinetobacter baumannii is a non-fermentative gram-negative coccobacill that is prevalent in intensive care units. Carbapenem resistant A.baumannii isolates have been reported worldwide. Oxasillinase beta-lactamase enzymes are involved in bacterial resistance to carbapenem. This study aimed to determine the prevalence of blaOXA-23 and blaOXA-24 genes in A. baumannii isolated from ...
[ 4 ] - بررسی فراوانی ژن‌های مقاوم به سیپروفلوکساسین qnrB و qnrA در جدایه‌های اشریشیاکلی جدا شده از عفونت ادراری در بیمارستان استهبان فارس
Introduction: Urinary tract infections(UTIs) are regarded as a serious health problem that affects millions of people per year. In fact, Escherchia coli causes about 75%-90% of UTIs. The wide usage of ciprofloxacin has led to an increase in the resistance to this bacterium. Therefore, this study aimed to evaluated frequency of qnrA and qnrB genes in E. coli strains isolated from UTIs at Imam Kh...
[ 5 ] - بررسی فعالیت فیزیکی دانشجویان مقطع علوم پایه پزشکی دانشگاه علوم پزشکی شهید صدوقی یزد سال تحصیلی 1394-1393
Introduction: Physical inactivity has been linked with many non-communicable diseases and it is now a major health problem in many countries. The aim of this research was to study the level of physical activity in the students at basic medical ssciences in Yazd Shahid Sadoughi University of Medical Sciences. Methods: This research was a cross sectional-descriptive study and its samplin...
[ 6 ] - بررسی وضعیت میزان رعایت حقوق بیماران و ضرورت آن از دیدگاه پرستاران بیمارستان های آموزشی شهر یزد در سال 1392
مقدمه: حقوق بیمار همان نیازهای جسمی، روانی و اجتماعی در شرایط خاصی است که فرد تحت درمان قرار می گیرد بنابراین وظیفه پرستار دفاع از حقوق و منافع بیمار است. هدف از این مطالعه بررسی رعایت حقوق بیماران توسط پرستاران و ارتباط آن با ضرورت توجه به این حقوق از دیدگاه آنان در بیمارستان های آموزشی شهر یزد می باشد. روش کار: در این مطالعه که به صورت توصیفی مقطعی انجام شد، تعداد 250 پرستار به صورت تصادفی ان...
[ 7 ] - بررسی فراوانی مصرف سیگار و مدل سازی عوامل پیشگویی کننده در دانش آموزان دبیرستانی شهر یزد در سال 1391
زمینه و هدف: با توجه به اهمیت مصرف سیگار به عنوان یک ریسک فاکتور مهم و قابل پیشگیری و به خصوص اهمیت شیوع بالای مصرف آن در دوران نوجوانی، این مطالعه با هدف شناخت عوامل زمینه ای گرایش به استعمال سیگار در نوجوانان دبیرستانی شهر یزد انجام شده است. روش بررسی: در این مطالعه توصیفی-تحلیلی، 450 نفر از دانش آموزان دبیرستانی شهر یزد به روش تصادفی خوشه ای انتخاب شدند. اطلاعات به کمک پرسشنامه محقق ساخته ا...
[ 8 ] - بررسی فراوانی میگرن در دانشجویان پزشکی دانشگاه علوم پزشکی شهید صدوقی یزد سال 1395
Background and purpose: Headache is one of the most common medical complaints and migraine is one of its major causes. The aim of this study was to investigate the prevalence of migraine in medical students in Shahid Sadoughi University of Medical Sciences. Materials and methods: This cross-sectional descriptive research was carried out in 400 medical students in Shahid Sadoughi University of ...
[ 9 ] - The Effect of Health-Based Intervention on Knowledge, Attitude and Practice of First-Grade High School Students
Introduction: Students' health of is of great importance because they account for a large part of community. Schools play an important role in the transfer of health information to students. The purpose of this study was to investigate the effect of a health-based intervention on the knowledge, attitude, and practice of high school students in Mehriz city. Methods: In this semi-experimenta...
[ 10 ] - Effect of Melatonin on Incidence Rate of Delirium in Elderly Patients Undergoing Open-Heart Surgery without a Pump: A Clinical Trial
Introduction: Delirium has been considered as the most common cognitive disorder after major surgery. Melatonin therapy is effective in reducing the incidence of delirium after open heart surgery with pain relief mechanism and adjustment of the sleep cycle and the absence of specific side effects. This study was conducted to determine the effectiveness of melatonin on prevention of delirium aft...
[ 11 ] - The Frequency of PON1 L55M Polymorphism and Measurement of Oxidative Stress Parameters (Superoxide Dismutase, Catalase, Thiol, and Carbonyl) in Neonates with G6PD Deficiency Compared to the Control Group
Introduction: Glucose-6-phosphate dehydrogenase deficiency is the most common enzyme disorder. This enzyme involved in maintaining the balance of active oxygen species and its defect causes oxidative damage. PON1 is an HDL-based glycosylated protein that prevents lipid peroxidation. In this study, the prevalence of PON L55M polymorphism in paraoxonase enzyme in neonates with a deficiency in G6P...
[ 12 ] - Frequency of Human Paraoxonase-1 Q192R Polymorphism and Measurement of Oxidative Stress Parameters in Infants with G6PD Deficiency
Background and Aims: This study aimed to investigate the frequency of Q192R polymorphism and oxidative stress markers in infants with glucose-6-phosphate dehydrogenase (G6PD) deficiency. Materials and Methods: This is a case-control study in which 60 male infants (2-4 months old) with G6PD deficiency along with 60 age- and sex-matched healthy neonates were included. The diagnosis of G6PD defic...
[ 13 ] - Seroprevalence of Toxoplasma gondii infection among young couples near marriage referred to prenatal counseling in Yazd city, central of Iran
Introduction: Toxoplasmosis is one of the most common causes of human parasitic infections and other warm-blooded vertebrates that has worldwide spread. The purpose of this study was to determine the mean level of Toxoplasmosis-related IgG, IgM in young couples at the time of marriage referring to Yazd Counseling Center 1396. Methods: In this study, 200 girls and boys were randomly selected to ...
[ 14 ] - Comparison between Efficiency of Poisson Regression Model and Negative Binomial Regression in the Analysis of Factors Affecting Mortality from Cardiovascular Diseases in Yazd Province in 2017
Introduction: Despite the advances in cardiovascular diseases, death caused by these diseases is still considered as the leading cause of mortality. In this study, some of the effective factors on the deaths caused by cardiovascular diseases were investigated Methods: This cross-sectional analytical study investigated the efficacy of Poisson regression models and negative binomial regres...
[ 15 ] - Protective Effects of Curcumin on Sperm and Stereological Parameters in Testes of Formaldehyde-Exposed NMRI Mice: An Experimental Study
Background and Aims: Formaldehyde (FA) exposure is an important cause of cellular injury and oxidative damage in testis, leading to infertility. This study aimed to assess the protective effects of curcumin on sperm and stereological parameters in testes from formaldehyde-exposed NMRI mice. Materials and Methods: At 6-8 weeks of age, 24 adult male NMRI mice weighing 30-35 g were categorized in...
[ 16 ] - Trend of Fetal Traffic injuries in Iran from 2009 to 2018
Introduction: According to the World Health Organization, Iran has a high level of deaths caused by traffic accidents. Assessment of the death trend and examination of the mortality rate can provide useful information for policy makers to take preventive measures and reduce the casualties caused by these accidents. In this study, the status and trend of mortality due to traffic accidents was in...
[ 17 ] - Frequency of fimH, papC, and aer in E. coli Strains Isolated from Patients with Urinary Tract Infection, and their Antibiotic Resistance Pattern
Introduction: E. coli is the predominant causes of urinary tract infection. Several virulence factors for bacterial infections in the urinary tract are required. In this study, we have considered several virulence factors in strains isolated from the patients with UTI in Yazd. Methods: In this cross-sectional study in 1394-1395, 146 strains isolated were collected from the patients with urinar...
[ 18 ] - Evaluation of the Status of Prophylactic Administration of Antibiotics in Surgery Department of Shahid Sadoughi Hospital of Yazd City in 2018
Introduction: surgical site infection is one of the most important causes of mortality and morbidity: use of the prophylactic antibiotic is one of the effective methods for its prevention, the present study aimed to investigate the status of prophylactic administration of antibiotics in Surgery Department of Shahid Sadoughi Hospital of Yazd City in 2018. Methods: this descriptive cross-section...
[ 19 ] - Effect of Genetically Modified Rice on Some Intestinal Microbial Flora in Rats
Background and purpose: Transgenic rice is a type of rice that its genetic sequence has been changed to improve its quantity and quality. Bt (Bacillus thuringiensis) transgenic rice expresses Cry1Ab protein and is named Tarom Molaii. There are no studies on the effect of this type of transgenic rice on gastrointestinal health in Iran, so, this study investigated the effect of Tarom Molaii tran...
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