در محمد کردی تمندانی
دانشگاه سیستان و بلوچستان
[ 1 ] - بررسی عوامل محیطی و ژنتیکی موثر بر محدودیت رشد داخل رحمی در جمعیت انسانی
محدودیت رشد داخل رحمی (IUGR) یکی از علل مهم و خاموش بیماری ها و مرگ و میر در جمعیت جنینی و نوزادان است، که در آن نوزادان پتانسیل رشدشان کمتر از حالت طبیعی می باشد. اصطلاح IUGR و کوچک برای سن حاملگی (SGA) اغلب بجای یکدیگر استفاده می شوند، گرچه تفاوت های ظریف بین این دو وجود دارد. IUGR/SGA در نتیجه اتیولوژی های مختلف شامل عوامل مادری، جفت و جنین بوجود می آید که اخیرا فاکتورهای ژنتیکی هم به آن اضا...
[ 2 ] - Analysis of IL-33 gene polymorphism (rs11792633 C/T) and risk of schizophrenia
Recently, inflammation has been found to be a significant factor in the development of Schizophrenia (SCZ). The aim of the present research was to investigate whether interleukin-33 (IL-33, OMIM: 608678) gene polymorphism (rs11792633, C/T) is associated with the development of SCZ or not.DNA was isolated from the serum of 70 patients with SCZ and 70 healthy controls. The PCR based method was us...
[ 3 ] - مطالعه ارتباط مقاومت به تراستوزوماب با بیان نسبی میکرو‌آر‌ان‌ای ۱۴۱ (miR-141 ) در سلول‌های انسانی سرطانی پستان BT-474
Background and Aim: Resistance to trastuzumab has been a critical barrier to targeted therapy of HER 2-positive (Human Epidermal Growth Factor Receptor 2) breast cancers. MicroRNAs (miRNAs) are known as decisive core regulators of drug resistance that modulate the epithelial-to-mesenchymal transition (EMT) and cancer-related immune responses. The present study aimed at examining the expression ...
[ 4 ] - Analysis of IL-33 Gene Polymorphisms (rs1157505C/G and rs11792633C/T) and the Risk of Tuberculosis in Southeastern Iran
Tuberculosis is a vagarious infectious disease that generally affects the lungs. Accordingly, in some cases, it can also affect the liver and kidney. Host genetic may affect tuberculosis caused by bacillus Mycobacterium tuberculosis. The main risk factors for the disease are a weakened immune system because of diabetes, some cancers, HIV/AIDS, severe kidney disease, cancer treatment, a...
[ 5 ] - Bone morphogenic protein receptor type 1a (BMPR1A) and Caveolin-1 associated with trastuzumab resistance of breast cancer cells
Trastuzumab is a specific monoclonal antibody used for therapeutic of the human epidermal growth factor receptor 2 (HER-2) -positive metastatic breast cancer. But, resistance to trastuzumab is a major obstacle in clinical efficiency. During the past years, several studies have been done to find the mechanisms contributing to trastuzumab resistance. Previous studies have highlighted that bone m...
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