جواد غفاری
دانشیار و فوق تخصص آلرژی و ایمونولوژی اطفال / گروه اطفال، دانشکده پزشکی، دانشگاه علوم پزشکی مازندران، ساری، ایران
[ 1 ] - بررسی کیفیت زندگی بیماران مبتلا به کهیر مزمن
مقدمه : هدف از این مطالعه ارزیابی اثرات کهیر مزمن بر کیفیت زندگی در افراد مراجعه کننده به کلینیک های آلرژیک طوبی و بوعلی سینا ساری می باشد. روش کار: این مطالعه توصیفی در سال 1388-1391 در کلینیک های آلرژی طوبی و بوعلی سینا شهر ساری انجام شد. پرسشنامه استاندارد مربوطه بر اساس اندکس کیفیت زندگی درماتولوژی (DLQI) انتخاب شده که حاوی مشخصات دموگرافیک، مشخصات بیماری و سوالات مختلف مربوط به کهیر مزمن ب...
[ 2 ] - تعیین ضریب هوشی کودکان دارای آسم متوسط در مقایسه با افراد سالم
مقدمه: آسم شایعترین بیماری مزمن در کودکان است. ضریب هوشی از شاخصه های ارزشیابی میزان کارائی افراد است. هدف از این مطالعه مقایسه ضریب هوشی بین بیماران کودک دارای آسم متوسط و کودکان مشابه سالم است. روش کار: این مطالعه مورد-شاهدی در مدت 8 ماه در سال 1390 در کلینیک طوبی شهر ساری انجام شده است. آزمون هوش وکسلر کودکان از طریق دو نیمه کردن برای هوشبهر کلی 97/ ، برای هوشبهر کلامی 97/ و برای هوشبهر...
[ 3 ] - شیوع آلرژنهای هوایی در بیماران دارای آسم،رینیت آلرژیک و کهیر مزمن
مقدمه آسم و رینیت آلرژیک به همراه کهیر از جمله بیماریهای مهم و شایع درهر جامعه ای هستند. هدف از این مطالعه تشخیص آلرژنهای هوایی از راه تست پوستی پریک در بیماران فوق در استان مازندران، ساری می باشد. روش کار در این مطالعه توصیفی-مقطغی تست پوستی پریک برای آلرژنهای هوایی در بیماران آسمی، رینیت آلرژیک یا هر دو و کهیر که ازنظر بالینی و تستهای پاراکلینیک اثبات شده اند و شرایط انجام تست پوستی پریک را د...
[ 4 ] - Asthma Burden in the Hospitalized Patients in North of Iran
Introduction: Asthma is a chronic inflammatory airway disease. Genetic and environmental factors have been important role in the induction of asthma. It's estimated that asthma affect 2.7 to 35.4% of child (in average 13.4%) in Iran. The aims of this study to assess the costs of asthma patients admitted in Boali hospital in Sari in the north of Iran. Patients and Methods: This descriptive study...
[ 5 ] - Mortality Rate in Pediatric Intensive Care Unit (PICU): A Local Center Experience
Introduction: Pediatric intensive care unit (PICU) has a specific location for management of children with serious and severe diseases. Methods: This is s crass-sectional – analytical Study was performed on all children admitted in Boali hospitals PICU from March 2010 to March 2012 (2 years). 937 patients were analyzed. Results: Out of 490 patient admitted in PICU (march2010 to march 2011), 35 ...
[ 6 ] - Hypersensitivity to House Dust Mite and Cockroach Is the Most Common Allergy in North of Iran
Background: Asthma and allergic rhinitis are among the most common diseases in the world. Objective: The aim of this study was to detect, by skin prick test, aeroallergens in allergic patients in Sari, Mazandaran in north of Iran. Methods: This is a prospective study of skin prick test of aeroallergens in asthma, allergic rhinitis and their combination with clinical diagnosis. Three hundred and...
[ 7 ] - آنژیوادم ارثی: تشخیص نامناسب، درمان ناکافی و گزارش 7 مورد از یک خانواده
Hereditary angioedema is a rare disorder of complement system which is often seen with autosomal dominant hereditary. Clinical characteristics include non- pruritic and non-pitting mucocutaneous edema that could involve all parts of the body. This study reports seven cases of hereditary angioedema with classical manifestations accompanied by low function of C1INH (type 2). One death occurred du...
[ 8 ] - آلرژنهای هوایی در تست پوستی بیماران مبتلا به آسم، رینیت آلرژیک، اگزما و کهیر مزمن در ایران
Asthma is a common chronic inflammatory of airways especially in childhood. Clinical manifestations include coughing, wheezing and sometimes dyspnea. Allergic rhinitis (AR) is a common nasal inflammatory disease in the world. Prevalence of AR is 10-40% in different regions of the world. Clinical manifestations of allergic rhinitis are sneezing, pruritus, congestion and rhino rhea. Etiologies of...
[ 9 ] - اثر ضدسرفه ای ترامادول در بیماران مبتلا به سیاه سرفه مزاحم
Background and purpose: Severe, tormenting and long-term coughing in patients suffering from pertussis causes disturbances in their and their families’ daily activity. The aim of this study was to evaluate the effect of Tramadol on alleviating coughing and severity of symptoms in pertussis patients. Materials and methods: Sixty cases of adult pertussis patients based on WHÔ and ÇDÇ guideline...
[ 10 ] - بررسی وضعیت اجسام خارجی ریوی در کودکان مراجعه کننده بهبیمارستان بوعلی سینا ساری و عوامل مرتبط با آن طی سال 1388-1380
Background and purpose: Although foreign body aspiration in children is uncommon but it is life-threatening in children under 3 years old. The aim of this study is to review the data records on nature, location and symptoms of foreign body aspiration, diagnostic method, and prediction for improving the health care knowledge and its prevention. Materials and methods:Children with suspected fo...
[ 11 ] - گزارش دو مورد اختلال حرکت اولیه مژک ها (گزارش مورد)
Primary ciliary dyskinesia and Kartagener's syndrome are rare genetic disorders. There is a ciliary dysfunction in these disorders that cause recurrent infections in respiratory and sinus tracts associated with dextrocardia, chronic vasomotor rhinitis and dextrocardia. The aim of this paper is to report two rare cases of Primary ciliary dyskinesia, including one case of primary ciliary dyskin...
[ 12 ] - بررسی بیماران مبتلا به نقص ایمنی اولیه مراجعه کننده به بیمارستان بوعلی سینا ساری از سال 85 لغایت 1388
Background and purpose: Primary immune-deficiencies (PID) are associated with a wide range of clinical disorders along with variable symptoms. The aim of this study was to evaluate and improve our knowledge regarding PID from patients that were referred to Booali Sina Hospital. Materials and methods: We evaluated all of PID`s that were referred to Booali Sina Hospital from their data recor...
[ 13 ] - گزارش یک مورد نابینایی ناشی از سندرم ویسکوت-آلدریچ (گزارش مورد)
Wiscott-Aldrich syndrome (WAS) is an x-linked immune-deficiency disorder associated with eczema, recurrent infections, and increased frequency of autoimmune diseases, malignancy and thrombocytopenia with small size platelet. Our case is an 11 year old from a non- related parent, who was admitted with abdominal pain (hematoma), lower extremities bleeding (ecchymosed) and vomiting. Also, he had...
[ 14 ] - بررسی ارتباط بین پره ترمی، نوع زایمان و طول مدت شیردهی با بروز آسم
Background and Purpose: Asthma is the most common chronic disease in children. The aim of this study was to investigate the relationship between pre-term delivery and breastfeeding with asthma. Materials and Methods: We studied 228 asthmatic patients who were referred to the Allergy Department in Children’s Medical Center (Tehran). Asthma was diagnosed based on the history, physical exam a...
[ 15 ] - معرفی یک مورد نادر از سندرم مارشال (PFAPA)
Fever is considered a common symptom in children. Periodic fever with less luadeuce produces additional complications. In this study, we present a rare periodic fever syndrome which contains aphthus stomatitis, pharyngitis and cervical adenitis (PFAPA) in a 3 year old child with typical symptoms. His fever was present for 2-4 days (100%), in addition, cervical adenitis & pharyngitis associate...
[ 16 ] - ارتباط کهیر مزمن با اتوایمونیتی تیروئید
Background and Purpose: chronic urticaria is a tormenter and does not have a known etiology. Association between chronic urticaria and thyroid auto-immunity has shown different results. The aim of this study is to evaluate the effect of Levo-thyroxine on the chronic urticaria and association between chronic urticaria with thyroid auto-immunity. Materials and Methods: In a prospective case-...
[ 17 ] - عوارض ناشی از تزریق ایمونوگلوبولین وریدی در بیماران با نقص ایمنی اولیه
Background and Purpose: Intravenous immunoglobulin is used for primary immunodeficiency disorders. There have been some reports that intravenous immunoglobulin causes side effects. The aim of this study was to investigate intravenous immunoglobulin side effects in immunodeficiency patients. Materials and Methods: The study utilized the data of 29 primary immunodeficiency patients that were...
[ 18 ] - Conjugate and 23-valent pneumococcal polysaccharide booster vaccination in asplenic patients with thalassemia major: A randomized clinical trial study
Background: Pneumococcal vaccine provides protection against invasive pneumococcal disease in population at risk. This study was conducted to compare the antibody response to 13-valent pneumococcal conjugate vaccine and 23-valent pneumococcal polysaccharide vaccine in patients with thalassemia major. Methods: A randomized cross-over clinical trial was performed on 50 asplenic patients with t...
[ 19 ] - Immune dysregulation in children with allergic asthma, a close relationship between IL-17 but not IL-4 or IFN-, and disease severity
Background : Allergic asthma is a chronic inflammatory disease of airway that often determined with degrees of inflammation, hypersensitivity, bronchial constriction and airway changes. Th1, Th2 and Th17 cells are the main cells involved in the pathophysiology of asthma. . Therefore, this study evaluated Th1, Th2, and Th17 cells functions by assessment the expression of INF-g, IL-4, and IL-17 g...
[ 20 ] - تأثیر خودمدیریتی بر کودکان 7 تا 12 ساله مبتلا به آسم
پیش‌زمینه و هدف: آسم شایعترین بیماری مزمن در دوران کودکی است و یکی از شایعترین علل مراجعه به اورژانس و بستری شدن در بیمارستان می‌باشد که عواقب بهداشتی و اقتصادی جدی به دنبال دارد. هدف از انجام این مطالعه، تعیین تأثیر خود مدیریتی بر آسم کودکان 7 تا 12 ساله می‌باشد. مواد و روش کار: تحقیق حاضر یک مطالعه نیمه تجربی است که به مدت 12 هفته بر روی 70 کودک سن مدرسه مبتلا به آسم مراجعه‌کننده به کلینیک ...
[ 21 ] - The Relationship Between Maternal Vitamin E and Progress of Children Asthma: A Review Article
Asthma is a chronic inflammatory respiratory disease. Nutritional conditions effects on allergic diseases such as asthma. The aim of this study is to find relation of maternal vitamin E and progression of children asthma. This is a review article searched in data base include Google, PubMed, SID, Irandoc, Scopus and up-to-date. Key words for search include maternal vitamin e, asthma, children ...
[ 22 ] - Comorbidities of pediatric asthma: A narrative review
Background: Asthma is one of the most common persistent inflammatory respiratory disorders. Comorbidities are relatively common in asthma. The aim of this review study was to find comorbid disorders in children with asthma. Methods: For the purpose of this review, we searched databases including Scopus, Google scholar, PubMed, SID, Irandoc and up-to-date. Key words for the search included chil...
[ 23 ] - Comorbidities in Patients with Chronic Urticaria; Clinical and Epidemiological Review Study
Background and purpose: Urticaria is a pruritic cutaneous disease characterized by weal and flare. Acute and chronic urticaria affects the quality of life. Some abnormalities are associate or comorbid with urticaria. The purpose of this study was to examine comorbid conditions in patients with urticaria. Materials and Methods: We searched in many databases including Google Scholar, PubMed, S...
[ 25 ] - Sensitization to Food and Aeroallergens in Patients with Asthma, Allergic Rhinitis, Eczema and Urticaria
Background and Aims: Allergic disorders such as asthma, urticaria, eczema, and allergic rhinitis are common worldwide, and allergens are the most common etiology and exacerbating factors. So, This study aimed to find the allergens in these patients with skin prick tests. Materials and Methods: All the allergic cases referred to an allergic clinic in the north of Iran were visited by an allergi...
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