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دانشیار گروه فارماکولوژی دانشکده داروسازی دانشگاه علوم پزشکی تبریز
[ 1 ] - تاثیر امواج فراصوت و دی‌اکسید تیتانیوم بر استافیلوکوکوس آرئوس و اشرشیاکلی در کشک مایع
کشک یکی از محصولات لبنی تخمیری مهم در ایران است که مستعد آلودگی به میکروبهای بیماریزا و فسادزا است. در این پژوهش تاثیرامواج فراصوت قدرت (130 وات، 20 کیلوهرتز) و دی اکسید تیتانیوم بر روی میکروارگانیسم‌های شاخص استافیلوکوکوس آرئوس (ATCC 29213) و اشرشیاکلی (DH 5-α) در کشک مایع بررسی شد. نتایج حاصل از آنالیز واریانس نشان داد تابش امواج فراصوت در سه بازه زمانی (5، 10 و 15 دقیقه) تاثیر معنی‌داری ( P...
[ 2 ] - Evaluation of Cytotoxic Effect and Antioxidant Activity of Grape Seed Extract, Crocin, and Phenytoin
Antioxidant compounds inhibit formation of free radicals, chelate catalytic metals, and scavenge free radicals in biological systems. In addition, antioxidants play a decisive role in prevention of numerous physiological dysfunctions, cancers, and metabolic disorders. This study sought to evaluate the antioxidant capacity and cytotoxic effect of grape seed extract (GSE), crocin (CRO), and pheny...
[ 3 ] - Genetic Variations of Tumor Necrosis Factor –α-308 and Lymphtoxin-α+252 in Non-Hodgkin Lymphoma and Acute Lymphoblastic Leukemia Patients
Objective(s): Non- Hodgkin lymphoma (NHL) and acute lymphoblastic leukemia (ALL) are two main hematological malignances which have been driven from lymphoid tissue. Genetic polymorphisms in tumor necrosis factor-α (TNF-α) -308 and lymphotoxin-α (LT-α) +252 may affect their transcription and expression which leads to their high plasma level. The frequency of the TNF-α (-308) and LT-...
[ 4 ] - Prevalence of PER and VEB Type Extended Spectrum Betalactamases among Multidrug Resistant Acinetobacter baumannii Isolates in North-West of Iran
Objective(s): Drug resistant Acinetobacter baumannii have emerged as a major problem in many hospitals and intensive care units. Various types of extended spectrum beta-lactamases (ESBLs) are responsible for resistance to beta- lactam antibiotics in different parts of the world. The objective of this study was to determine the prevalence of integron class1 (INT 1) and ESBL types PER-1, PER-2 ...
[ 5 ] - Cloning and Expression of the Variable Regions of Anti-EGFR Monoclonal Antibody in E. coli for Production of a Single Chain Antibody
Background:Epidermal growth factor receptor (EGFR) overexpression is a characteristic of several malignancies and could be considered as an excellent target for designing specific inhibitors such as anti-EGFR monoclonal antibodies for cancer therapy. Drawbacks exerted by large sizes of full-length antibodies have lead to the development of single chain antibodies, which benefit from having smal...
[ 6 ] - Protective Properties of Nontoxic Recombinant Exotoxin A (Domain I-II) Against Pseudomonas aeruginosa Infection
Background: Antibiotic resistance and the need for long-term treatments especially for chronic infections necessitate the development <span style="fon...
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