فرهود نجفی
هیئت علمی پژوهشگاه علوم و فناوری رنگ
[ 1 ] - تاثیر نانولوله های کربنی بر انتقال جرم و هیدرودینامیک در یک سیستم استخراج مایع- مایع
در این پژوهش یک سیستم تک قطره استخراج مایع- مایع در حضور نانولوله های کربنی مطالعه شد. نانولوله های کربنی تاثیر چشمگیری در افزایش ضریب انتقال حرارت دارند و با توجه به تشابه انتقال حرارت و انتقال جرم، این نانولوله ها در یک سیستم انتقال جرم بررسی شدند. همچنین به‌منظور تعیین میزان تأثیر ساختار مولکولی بر ضریب انتقال جرم، نانولوله¬های کربنی با نانو ذرات سیلیکا مقایسه شدند. استیک اسید، تولوئن و نانو...
[ 2 ] - Nano packaged Tamoxifen and Curcumin; effective formulation against sensitive and resistant MCF-7 cells
Tamoxifen is routinely used for treatment of Estrogen-positive breast carcinoma. Approximately, 50% of patients with metastatic cancer will develop resistance to Tamoxifen. In this research, Tamoxifen was combined with the anti-cancer compound Curcumin. Diblock nanopolymer was used to package the new formulation of Curcumin and Tamoxifen. Anti-cancer efficacy of the obtained compound was evalua...
[ 3 ] - SRL-coated PAMAM dendrimer nano-carrier for targeted gene delivery to the glioma cells and competitive inhibition by lactoferrin
Glioma, as a primary tumor of central nervous system, is the main cause of death in patients with brain cancer. Therefore, development of an efficient strategy for treatment of glioma is worthy. The aim of the current study was to develop a SRL peptide-coated dendrimer as a novel dual gene delivery system for targeting the LRP receptor, an up-regulated gene in both BBB and glioma cells. To perf...
[ 4 ] - Dendrosomal nano-curcumin; The novel formulation to improve the anticancer properties of curcumin
Curcumin is a hydrophobic polyphenol extracted from the plant curcuma longa with establishedanticancer properties. However, curcumin benefits have been impaired by its very low watersolubility, low absorption, rapid metabolism and clearance from the body. Recently,nanotechnology promises to be helpful in development of drugs delivery systems by recentadvances in macromolecular design of nanocar...
[ 5 ] - Nano packaged Tamoxifen and Curcumin; effective formulation against sensitive and resistant MCF-7 cells
Tamoxifen is routinely used for treatment of Estrogen-positive breast carcinoma. Approximately, 50% of patients with metastatic cancer will develop resistance to Tamoxifen. In this research, Tamoxifen was combined with the anti-cancer compound Curcumin. Diblock nanopolymer was used to package the new formulation of Curcumin and Tamoxifen. Anti-cancer efficacy of the obtained compound was evalua...
[ 6 ] - SRL-coated PAMAM dendrimer nano-carrier for targeted gene delivery to the glioma cells and competitive inhibition by lactoferrin
Glioma, as a primary tumor of central nervous system, is the main cause of death in patients with brain cancer. Therefore, development of an efficient strategy for treatment of glioma is worthy. The aim of the current study was to develop a SRL peptide-coated dendrimer as a novel dual gene delivery system for targeting the LRP receptor, an up-regulated gene in both BBB and glioma cells. To perf...
[ 7 ] - مروری بر شناسایی رزین های دی ترپنویید در ورنی آثار هنری به روش طیف‌سنجی مادون قرمز تبدیل فوریه
Making varnishes from diterpenoid resins with the several orders had been common in Iran from 12th Century and it has also been reported in Europe from medieval ages. Identification of these resins in old samples and investigation of their degradations through ageing process have performed by various methods. FTIR spectrometry has always been of interest to researchers because it is cheap, avai...
[ 8 ] - قابلیت ریسندگی و خواص کششی الیاف پلی (اتیلن ترفتالات) با اختلاط سیالات یونی پلیمری حین فرایند مذاب ریسی
سیالات یونی با داشتن خواص ویژه ای چون دمای ذوب کم، پایداری گرمایی زیاد، رسانایی الکتریکی زیاد و سایر خواص به ویژه به عنوان حلال های دوست دار محیط زیست استفاده می شوند. مطالعات نشان می دهد، استفاده از این مواد در صنعت نساجی بسیار جدید است. به طوری که استفاده از سیال یونی در فرایند محلول ریسی الیاف ویسکوز به عنوان حلال سلولوز تا این زمان، تنها کاربرد صنعتی این ماده در صنعت نساجی بوده است. ...
[ 9 ] - بررسی کارایی نانوکامپوزیت عاملدارشده PAMAM-GO در حذف نیترات از محیط‌های آبی
به دلیل حلالیت بسیار زیاد نیترات در آب، روش‌های متداول تصفیه قادر به حذف آن نیستند. این پژوهش با هدف تعیین کارایی نانوکامپوزیت عاملدار شده PAMAM-Go به‌منظور حذف نیترات از محیط‌های آبی در مقیاس آزمایشگاهی و به‌صورت پایلوت و برای اولین بار در ایران و جهان انجام شد. در این پژوهش سنتز گرافن اکساید به‌روش اصلاح شده هومر صورت...
[ 10 ] - Facile Synthesis and Characterization of Ibuprofen-mesoporous Hydroxyapatite Nanohybrid as a Sustained Drug Delivery System
The present study deals with the fabrication of ibuprofen-mesoporous hydroxyapatite (IBU-MHA) particles via the incorporation of ibuprofen (IBU)—as a nonsteroidal anti-inflammatory drug—into mesoporous hydroxyapatite nanoparticles (MHANPs) using an impregnation process, as a novel drug delivery device. MHANPs were synthesized by a self-assembly process using cetyltrimethylammonium bromide (CTAB...
[ 11 ] - Facile Synthesis and Characterization of Ibuprofen-mesoporous Hydroxyapatite Nanohybrid as a Sustained Drug Delivery System
The present study deals with the fabrication of ibuprofen-mesoporous hydroxyapatite (IBU-MHA) particles via the incorporation of ibuprofen (IBU)—as a nonsteroidal anti-inflammatory drug—into mesoporous hydroxyapatite nanoparticles (MHANPs) using an impregnation process, as a novel drug delivery device. MHANPs were synthesized by a self-assembly process using cetyltrimethylammonium bromide (CTAB...
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