آزاده ابراهیم حبیبی
دانشیار مرکز تحقیقات غدد درون ریز و متابولیسم دانشگاه علوم پزشکی تهران، تهران، ایران
[ 1 ] - اثرات بیوشیمیایی فروکتوز بر رژیم چاقی در موش‌های بالغ نر نژاد NMRI
مقدمه: مصرف بیش از حد شیرین کننده‌های مصنوعی با افزایش شاخص توده بدنی و میزان ابتلا به بیماری‌های قلبی عروقی، تنگی‌نفس، آرتروز، دیابت نوع دو، سکته مغزی، فشارخون بالا همراه است و اثرات نامطلوب متابولیکی را نشان می‌دهد. هدف از این تحقیق تاثیر فروکتوز روی چاقی و پارامترهای بیوشیمیایی در موش‌های نر بالغ نژادNMRI است. مواد و روش‌ها: این مطالعه طی دو مرحله انجام شد. در مرحله اول تیمار به مدت 8 هفت...
[ 2 ] - Effects of Dimethyl Sulfoxide and Mutations on the Folding of Abeta(25-35) Peptide: Molecular Dynamics Simulations
The 25-35 fragment of the amyloid β (Aβ) peptide is a naturally occurring proteolytic by-product of its larger parent molecule that retains the amyloid characteristics and toxicity of the full length parent molecule. Aggregation of this peptide occurs rapidly in aqueous solutions and thus characterization of its folding process is very difficult. In the present study, early stages of Aβ(25–35) ...
[ 3 ] - UV Spectrophotometric Determination and Validation of Hydroquinone in Liposome
The method has been developed and validated for the determination of hydroquinone in liposomal formulation. The samples were dissolved in methanol and evaluated in 293 nm. The validation parameters such as linearity, accuracy, precision, specificity, limit of detection (LOD) and limit of quantitation (LOQ) were determined. The calibration curve was linear in 1-50 µg /mL range of hydroquinone an...
[ 4 ] - UV Spectrophotometric Determination and Validation of Hydroquinone in Liposome
The method has been developed and validated for the determination of hydroquinone in liposomal formulation. The samples were dissolved in methanol and evaluated in 293 nm. The validation parameters such as linearity, accuracy, precision, specificity, limit of detection (LOD) and limit of quantitation (LOQ) were determined. The calibration curve was linear in 1-50 µg /mL range of hydroquinone an...