زهره مظاهری
. استادیار گروه علوم تشریح دانشکده پزشکی دانشگاه تربیت مدرس. تهران. ایران
[ 1 ] - تاثیر تمرین ورزشی تناوبی شدید بر بیان ژن مایونکتین عضلانی و مقاومت به انسولین رت‌های نر بالغ نژاد ویستار
هدف از پژوهش حاضر بررسی چهار هفته فعالیت ورزشی تناوبی شدید بر بیان ژن مایونکتین عضلانی و مقاومت به انسولین رت‌های نر بالغ نژاد ویستار است. در این پژوهش 14 سر رت نر بالغ از نژاد ویستار (با سن هشت هفته)، به صورت تصادفی به دو گروه هفت تایی شاهد و تمرین تقسیم شدند.گروه تمرین، چهار هفته تمرین تناوبی شدید دویدن روی نوارگردان ( پنج جلسه در هفته) انجام دادند و گروه شاهد هیچگونه تمرینی نداشت. عضله نعل...
[ 2 ] - تأثیر تمرین تناوبی شدید بر بیان ژن CTRP15 عضلانی و انتقال‌دهنده‌های اسید چرب آدیپوسیت‌ها در موش‌های صحرایی نژاد ویستار
هدف پژوهش حاضر بررسی چهار هفته فعالیت ورزشی تناوبی شدید بر بیان ژن CTRP15 عضلانی و انتقال‌دهنده‌های اسید چرب آدیپوسیت‌ها در موش‌های صحرایی بالغ نژاد ویستار بود. در این پژوهش، 14 سر موش صحرایی نر بالغ از نژاد ویستار (با سن هشت هفته) به‌صورت تصادفی ساده به دو گروه هفت‌‌تایی شاهد و تمرین تقسیم شدند. گروه تمرین چهار هفته تمرین تناوبی شدید دویدن روی نوارگردان (پنج جلسه در هفته، از سرعت 35 تا 55 متر ...
[ 3 ] - Male germ-like cell differentiation potential of human umbilical cord Wharton’s jelly-derived mesenchymal stem cells in co-culture with human placenta cells in presence of BMP4 and retinoic acid
Objective(s):Mesenchymal stem cells (MSCs) derived from Wharton’s jelly (WJ-MSCs) are now much more appealing for cell-based infertility therapy. Hence, WJ-MSCs differentiation toward germ layer cells for cell therapy purposes is currently under intensive study. Materials and Methods: MSCs were isolated from human Wharton’s jelly and treated with BMP4, retinoic acid (RA) or co-cultured on huma...
[ 4 ] - Feasibility assessment of in vitro chemoresponse assay on stereotactic biopsies of glioblastoma multiforms: a step towards personalized medicine
Objective(s):P In vitro chemosensitivity and resistance assays (CSRAs) are a promising tool for personalized treatment of glioblastoma multiform (GBM). These assays require a minimum of 1 to 2 g of tumor specimen for testing, but this amount is not always accessible. We aimed to assess the feasibility and validity of utilizing stereotactic biopsies of GBM in CSRAs. Materials and Methods: Single...
[ 5 ] - اثر حفاظتی عصاره هیدروالکلی دارچین بر تغییرات بافت بیضه و ظرفیت باروری موش های صحرایی نر مواجهه یافته با استرس صدا
Background and Aim: So far, few studies have assessed the effect of noise on fertility capacity thus this study aimed to evaluate the possible protective effects of cinnamon extract on testicular tissue changes and fertility capacity in male rats exposed to noise stress. Materials and Methods: In this experimental study, 40 male rats were randomly divided into 5 experimental groups. Grou...
[ 6 ] - Case Report: Unilateral Incompletely Duplicated Ureter without any Accessory Renal Artery
There are often duplicated ureter with types of congenital anomalies and associated clinical complications. The unilateral duplicated ureter was observed as an incidence result in usual dissection. During routine dissection of the body of an adult male with middle-aged 40-50 year old, the duality of unilateral incompletely ureter was seen in above. Two branches of ur...
[ 7 ] - Establishment of Oxidative Stress Modeling during Spermatogonial Stem Cells Cultivation Treated with Different Doses of H2O2
Introduction: Nowadays, spermatogonial stem cells (SSCs) cultivation has been used by many researchers as an effective tool for infertility treatments. Oxidative conditions can be effective on cell proliferation and differentiation of these cells. So, the aim of this study was to establish oxidative stress model for antioxidant activity of some drugs investigation during SSCs in vitro culture. ...
[ 8 ] - The Effects of Calligonum Extract and Low-intensity Ultrasound on Motility, Viability, and DNA Fragmentation of Human Frozen-Thawed Semen
Background: The study aimed to evaluate the impact of Calligonum extract and US radiation on sperm parametersof cryopreserved human semen samples.Materials and Methods: In this experimental study, twenty-five semen specimens were obtained from healthy semendonors and incubated in human tubal fluid (HTF) medium supplemented with 10% human serum albumin (HSA) for45 minutes...
[ 9 ] - Effects of hepatitis C virus NS3 protein on expression of heat shock protein 70 and Glypican3 as the markers of hepatocellular carcinoma
Background and Aims: Hepatitis C virus (HCV) infection is an important risk factor for the development of liver cancer. The HCV NS3 protein plays a key role in the virus life cycle and can affect normal cellular activities, such as cell proliferation, cell death, and cell signaling pathways. Moreover, it may influence malignancy development. Two cellular genes, heat shock protein 70 (HSP70) and...
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