Gholizadeh , Monireh
Department of Immunology, Pasteur Institute of Iran, Tehran, Iran-Department of Medical Biotechnology, Faculty of Advanced Medical sciences, Tabriz University of Medical sciences, Tabriz, Iran,
[ 1 ] - Design and development of CAR-T cells for cancer therapy
Introduction: Today, treatment with CAR-T cells is accepted as an effective treatment for blood malignancies. CAR-T cells are autologous T cells that are engineered by gene transfer techniques to express a chimeric antigen receptor (CAR). Despite the promising results and the approval of six CAR-T cell products; these products have not yet been approved for solid tumors. In addition, the high c...
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