Martin Mortazavi
California Institute of Neuroscience, Los Angeles, Ca, USA
[ 1 ] - Application of 5-ALA Fluorescence-Guided Resection in Patients Suffering from High-Grade Gliomas: Report of 30 Consecutive Cases and a Literature Review
Background and Importance: The extent of resection seems a solid prognostic factor in patients suffering from high-grade gliomas (HGGs). When administered orally, 5-ALA is exclusively converted by malignant cells into protoporphyrin IX (PPIX), identifying contrast-enhancing glial lesions under blue 400-nm light. The authors thoroughly assess the efficacy, accuracy, and safety profile of 5-ALA-g...
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