Hashemi, Seyedeh Mahdieh

[ 1 ] - Preparation and evaluation of 99mTc-labeled zidovudine function as an analog of thymidine in the diagnosis of human lung cancer cells

Introduction: Labeled nucleotide detectors provide a basis for measuring cell division. Zidovudine is a prodrug that is phosphorylated by cellular enzymes at the 5ʹ position and converted to active triphosphate. Zidovudine triphosphate interferes with the reverse transcriptase enzyme and lengthens the viral DNA strand. Materials and Methods: Ethyl-2-propynyl acetate and 2-amino-N-propynyl benza...