Saeed Keshavarz

[ 1 ] - Effect of Aerobic Exercise on the Expression of PGC-1α and SIRT-1 in Cardiac Muscle of Diabetic Male Wistar Rats

Background: Type 2 diabetic patients have an abnormally high rate of mortality due to cardiovascular diseases. Given the adverse impact of diabetes on in heart cells and the role of exercise on mitochondrial biogenesis signaling, this study investigated the effect of eight weeks of aerobic exercise on PGC-1a and SIRT-1 gene expression in the myocardium of diabetic male Wistar rats. Materials a...