Aali, Ehsan
Qazvin university of Medical Sciences
[ 1 ] - The effects of chronic administration of pioglitazone on learning and memory in streptoztocin rat model of Alzheimer’s disease
Background: Alzheimer’s disease (AD) is a chronic neurodegenerative disease characterized by abnormal protein accumulation, synaptic dysfunction, and cognitive impairment. Peroxisome proliferator-activated gamma receptors (PPARγ) play a crucial role in regulating insulin sensitivity and may serve as potential therapeutic targets for AD. Pioglitazone (Piog) as a PPARγ agonist reduce β-amyloid ...
[ 2 ] - Inhibitory Effect of Ferula persica, Ginkgo biloba, Nelumbo nucifera, and Dicyclomine on the Activity of Pancreatic Lipase
Background and purpose: Pancreatic lipase is a major digestive enzyme in digestion and absorption of fats. Inhibition of the pancreatic lipase activity has always been one of the goals of researchers to control obesity and related disorders. Current inhibitory agents have several side effects. The aim of this study was to investigate the inhibitory effect of Ferula persica, Ginkgo biloba, Nel...
[ 3 ] - The effects of oral silver nanoparticles and propolis on level of lipid peroxidation in male Wistar rats
Objective: Oxidative stress is a leading factor in the development of silver nanoparticle-induced toxicity. This study evaluated the effects of oral prescription of different doses of silver nanoparticles and propolis on lipid peroxidation in male Wistar rats. Materials and Methods: The male wistar rats were randomly divided into four groups. Control group and three different treatment groups ...