Esmaeil Moghaddam, Sogand

Student Research Committee, Rafsanjan University of Medical Sciences, Rafsanjan, Iran

[ 1 ] - Pretreatment effects of metformin on behavioral manifestations of global ischemia/reperfusion injury in rats

Introduction: Metformin (MET) as an oral antidiabetic drug has pleiotropic effects such as antioxidative and neuroprotective properties. In the current study we aimed to investigate the probable effects of Pretreatment MET therapy in global ischemia-reperfusion in rats. Materials and Methods: In this study, 40 male Wistar rats (200-220 g) were used. Animals were randomly divided into four g...