Azad M

[ 1 ] - P-85: How a Frame Shift Caused by a Single Base Deletion In SEPT12 Gene Shed Lights As a Polymorphism

Background: Septins are members of highly conserved polymerizing GTP binding proteins well described in the animal kingdom. 14 Septin proteins have been characterized in humans (SEPT1-SEPT14), some of which are tissue-specific. All of 14 genome-mapped human septins contain a highly conserved central GTP-binding domain which is very critical in GTPase signaling properties as well as oligomerizat...