Pirjamali L

[ 1 ] - P-130: Designing and Construction of An Appropriate Eukaryotic Expression Vector to Generate Soluble Form of Human Hyaluronidase Type PH20 in Cell Culture Feasible for Application in IVF and ICSI

Background: The hyaluronidases are the enzymes hydrolyze β-1, 4 glycosidic linkage of hyaluronan. Hyaluronan is a polymer consisting of a repeating disaccharide unit found in cumulus ovuforus complex, semen liquid and other tissue. Addition to hydrolyzing the hyaluronan, hyaluronidase can penetrate through the cumulus cells layer that surrounds the oocyte, thus it terms spreading factor. Moreov...