Kuroshli Z

[ 1 ] - P-214: Parental Contribution of HLA-G*0106 and G*0105N to Repeated Implantation Failure

Background: HLA-G, as a tolerogenic molecule, expressed in cytotrophoblast cells and playing an important role in the suppression of the immune response in maternal decidua. Today Interaction of the extracellular domains of HLA-G protein with cell receptors of immune system, including CD8, LILRB1, LILRB2 and killer cell immunoglobulin-like receptor KIR2DL4, was well known. Materials and Methods...

[ 2 ] - P-203: Investigating Association of HLA-G Gene Polymorphisms and Failed Implantation in Human Embryos

Background: HLA-G is a non-classical human leukocyte antigen expressed primarily in fetal tissues at the maternal-fetal interface. The unique structure of HLA-G molecule permits a restricted peptide presentation and allows the modulation of the immune system. There is now general agreement that HLA-G is an important immunotolerant molecule with the capability of inhibiting immune cell functions...

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Bazrgar M 2