Maryam Shahhoseini
Department of Genetics, Reproductive Biomedicine Research Center, Royan Institute for Reproductive Biomedicine, ACECR, Tehran, Iran.
[ 1 ] - The Effect of Imbalanced Progesterone Receptor-A/-B Ratio on Gelatinase Expressions in Endometriosis
Objective Objective: Gelatinases degrade extracellular matrix (ECM) components to make physiological remodeling and contribute to pathological tissue destruction in endometriosis. It is known that gelatinases’ function is resistant to suppression by progesterone in endometriosis. The ability of progesterone to impact gene expression depends on the progesterone receptor-A/-B (PR-A/PR-B) ratio. A...
[ 2 ] - O-28: Role of HOX Family Related Genes in Pain Generation of Endometriosis Patients
Background Endometriosis is a common gynecological disease, can cause severe pelvic pain. Studies demonstrated the presence of sensory nerve fibers in endometrium of endometriosis patient. Nevertheless, no information is available on mechanisms of sensory nerve formation in eutopic or ectopic lesions. Since HOX genes have important roles in both reproductive tract and nerve growth, we decided t...
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