Amri, Jamal

MSc in Biochemistery, Traditional and Complementary Medicine Research Center, Arak University of Medical Sciences, Arak, Iran

[ 1 ] - Effects of Pre-pregnancy Chronic Valproate Administration in Female Rats on Avoidance Memory and Hippocampal Gene Expression of Offspring

Background and purpose: Valproic acid derivatives are histone deacetylases (HDACs) inhibitors. HDACs are important in epigenetic processes. Some epigenetic modifications are inherited. This study aimed at investigating the intergenerational effects of pre-pregnancy chronic valproate consumption on offspring. Materials and methods: In this experimental study, twelve female Wistar rats were rand...

نویسندگان همکار